Critical Care Management of Acute Venous Thromboembolism: Integrating Pharmacotherapy, Thrombectomy, and Temporary Mechanical Support
Venous thromboembolism (VTE), which includes pulmonary embolism and deep vein thrombosis, carries significant morbidity and mortality risks, and is conventionally managed with anticoagulation. In recent years, notable progress has been made in the therapeutic options available for the acute treatmen...
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| Format: | Article |
| Language: | English |
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Radcliffe Medical Media
2024-11-01
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| Series: | US Cardiology Review |
| Online Access: | https://www.uscjournal.com/articleindex/usc.2024.11 |
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| author | Nazli Okumus Ashley Park Eugene Yuridistky James M Horowitz Michael A Solomon |
| author_facet | Nazli Okumus Ashley Park Eugene Yuridistky James M Horowitz Michael A Solomon |
| author_sort | Nazli Okumus |
| collection | DOAJ |
| description | Venous thromboembolism (VTE), which includes pulmonary embolism and deep vein thrombosis, carries significant morbidity and mortality risks, and is conventionally managed with anticoagulation. In recent years, notable progress has been made in the therapeutic options available for the acute treatment of VTE. The heterogeneity within pulmonary embolism, spanning a wide spectrum of risks, underscores the critical need for precise risk stratification, particularly in identifying individuals prone to right heart failure and increased mortality. This review navigates the transformative developments in VTE approaches, focusing on the diagnosis and management of acute VTE in the critical care setting. It encompasses developing critical care approaches to intermediate- and high-risk pulmonary embolism, the treatment of right heart failure, and the integration of mechanical circulatory support, providing comprehensive insights into risk stratification, emerging interventions, and evolving treatment strategies. It is important to note that some of the novel therapies are still under clinical trials and, despite promising reports, are not yet considered standard of care. |
| format | Article |
| id | doaj-art-e103332c1501434c9ccf8aeea0d08632 |
| institution | DOAJ |
| issn | 1758-3896 1758-390X |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Radcliffe Medical Media |
| record_format | Article |
| series | US Cardiology Review |
| spelling | doaj-art-e103332c1501434c9ccf8aeea0d086322025-08-20T02:39:23ZengRadcliffe Medical MediaUS Cardiology Review1758-38961758-390X2024-11-011810.15420/usc.2024.11Critical Care Management of Acute Venous Thromboembolism: Integrating Pharmacotherapy, Thrombectomy, and Temporary Mechanical SupportNazli Okumus0Ashley Park1Eugene Yuridistky2James M Horowitz3Michael A Solomon4Department of Cardiovascular Medicine, Allegheny Health Network, Pittsburgh, PACritical Care Medicine Department, National Institutes of Health Clinical Center, Bethesda, MDDivision of Cardiology, Department of Medicine, NYU Grossman School of Medicine, New York, NYDivision of Cardiology, Department of Medicine, NYU Grossman School of Medicine, New York, NYCritical Care Medicine Department, National Institutes of Health Clinical Center, Bethesda, MD; Cardiovascular Branch, National Heart, Lung, and Blood Institute of the National Institutes of Health, Bethesda, MDVenous thromboembolism (VTE), which includes pulmonary embolism and deep vein thrombosis, carries significant morbidity and mortality risks, and is conventionally managed with anticoagulation. In recent years, notable progress has been made in the therapeutic options available for the acute treatment of VTE. The heterogeneity within pulmonary embolism, spanning a wide spectrum of risks, underscores the critical need for precise risk stratification, particularly in identifying individuals prone to right heart failure and increased mortality. This review navigates the transformative developments in VTE approaches, focusing on the diagnosis and management of acute VTE in the critical care setting. It encompasses developing critical care approaches to intermediate- and high-risk pulmonary embolism, the treatment of right heart failure, and the integration of mechanical circulatory support, providing comprehensive insights into risk stratification, emerging interventions, and evolving treatment strategies. It is important to note that some of the novel therapies are still under clinical trials and, despite promising reports, are not yet considered standard of care.https://www.uscjournal.com/articleindex/usc.2024.11 |
| spellingShingle | Nazli Okumus Ashley Park Eugene Yuridistky James M Horowitz Michael A Solomon Critical Care Management of Acute Venous Thromboembolism: Integrating Pharmacotherapy, Thrombectomy, and Temporary Mechanical Support US Cardiology Review |
| title | Critical Care Management of Acute Venous Thromboembolism: Integrating Pharmacotherapy, Thrombectomy, and Temporary Mechanical Support |
| title_full | Critical Care Management of Acute Venous Thromboembolism: Integrating Pharmacotherapy, Thrombectomy, and Temporary Mechanical Support |
| title_fullStr | Critical Care Management of Acute Venous Thromboembolism: Integrating Pharmacotherapy, Thrombectomy, and Temporary Mechanical Support |
| title_full_unstemmed | Critical Care Management of Acute Venous Thromboembolism: Integrating Pharmacotherapy, Thrombectomy, and Temporary Mechanical Support |
| title_short | Critical Care Management of Acute Venous Thromboembolism: Integrating Pharmacotherapy, Thrombectomy, and Temporary Mechanical Support |
| title_sort | critical care management of acute venous thromboembolism integrating pharmacotherapy thrombectomy and temporary mechanical support |
| url | https://www.uscjournal.com/articleindex/usc.2024.11 |
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