Application of CRISPR Technology in Plant Improvement: An Update Review

Clustered regularly interspaced short palindromic repeats/CRISPR-associated protein 9 (CRISPR/Cas9) stands as a major technique in genetic engineering, offering innumerable applications for enhancing agricultural and horticultural crops. It contributes significantly to improving quality traits, mana...

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Main Authors: Himanshu Saini, Avantika Devrani, Gideon Synrem, null Priyanka
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Advances in Agriculture
Online Access:http://dx.doi.org/10.1155/aia/4578877
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author Himanshu Saini
Avantika Devrani
Gideon Synrem
null Priyanka
author_facet Himanshu Saini
Avantika Devrani
Gideon Synrem
null Priyanka
author_sort Himanshu Saini
collection DOAJ
description Clustered regularly interspaced short palindromic repeats/CRISPR-associated protein 9 (CRISPR/Cas9) stands as a major technique in genetic engineering, offering innumerable applications for enhancing agricultural and horticultural crops. It contributes significantly to improving quality traits, managing biotic and abiotic stresses, and extending shelf life. Several genes, such as Cry genes or protease inhibitors and trypsin inhibitors, have been utilized to confer resistance against insect pests and diseases. This technique finds extensive application in medicine, agricultural, and horticultural crops. CRISPR/Cas9 has been successfully implemented in tomato, petunia, grapes, apple, and citrus, yielding promising results. For instance, in tomato, CRISPR/Cas9 has been employed with the Agrobacterium gene transfer method to provide resistance against powdery mildew disease. This review presents a comprehensive overview of CRISPR/Cas9 applications and achievements in agricultural and horticultural crops. Overall, this review highlights the potential applications of CRISPR technology in plant improvement, with limitations and challenges including off-target mutations, size of the CRISPR/Cas9 system, delivery, and bio-safety regulations to improve a variety of crop traits, including yield, quality, stress tolerance, disease, and herbicide resistance. It can also be used to speed up crop improvement compared to conventional breeding.
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spelling doaj-art-e10331bb5b624de59f12d85259576c362025-08-20T02:54:00ZengWileyAdvances in Agriculture2314-75392025-01-01202510.1155/aia/4578877Application of CRISPR Technology in Plant Improvement: An Update ReviewHimanshu Saini0Avantika Devrani1Gideon Synrem2null Priyanka3School of Applied Natural ScienceSchool of AgricultureSchool of AgricultureSchool of AgricultureClustered regularly interspaced short palindromic repeats/CRISPR-associated protein 9 (CRISPR/Cas9) stands as a major technique in genetic engineering, offering innumerable applications for enhancing agricultural and horticultural crops. It contributes significantly to improving quality traits, managing biotic and abiotic stresses, and extending shelf life. Several genes, such as Cry genes or protease inhibitors and trypsin inhibitors, have been utilized to confer resistance against insect pests and diseases. This technique finds extensive application in medicine, agricultural, and horticultural crops. CRISPR/Cas9 has been successfully implemented in tomato, petunia, grapes, apple, and citrus, yielding promising results. For instance, in tomato, CRISPR/Cas9 has been employed with the Agrobacterium gene transfer method to provide resistance against powdery mildew disease. This review presents a comprehensive overview of CRISPR/Cas9 applications and achievements in agricultural and horticultural crops. Overall, this review highlights the potential applications of CRISPR technology in plant improvement, with limitations and challenges including off-target mutations, size of the CRISPR/Cas9 system, delivery, and bio-safety regulations to improve a variety of crop traits, including yield, quality, stress tolerance, disease, and herbicide resistance. It can also be used to speed up crop improvement compared to conventional breeding.http://dx.doi.org/10.1155/aia/4578877
spellingShingle Himanshu Saini
Avantika Devrani
Gideon Synrem
null Priyanka
Application of CRISPR Technology in Plant Improvement: An Update Review
Advances in Agriculture
title Application of CRISPR Technology in Plant Improvement: An Update Review
title_full Application of CRISPR Technology in Plant Improvement: An Update Review
title_fullStr Application of CRISPR Technology in Plant Improvement: An Update Review
title_full_unstemmed Application of CRISPR Technology in Plant Improvement: An Update Review
title_short Application of CRISPR Technology in Plant Improvement: An Update Review
title_sort application of crispr technology in plant improvement an update review
url http://dx.doi.org/10.1155/aia/4578877
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