Complications and risk factors of endoscopic third ventriculostomy: A 10-year single-centre study and systematic literature review

Introduction: Endoscopic third ventriculostomy is considered a safe and low-risk treatment of obstructive hydrocephalus. No systematic review has been conducted recently to establish benchmarks for success and complication rates. This knowledge gap makes it difficult to evaluate local institutional...

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Main Authors: Einar Naveen Møen, Christian André Helland, Rupavathana Mahesparan
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Brain and Spine
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Online Access:http://www.sciencedirect.com/science/article/pii/S2772529425001109
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author Einar Naveen Møen
Christian André Helland
Rupavathana Mahesparan
author_facet Einar Naveen Møen
Christian André Helland
Rupavathana Mahesparan
author_sort Einar Naveen Møen
collection DOAJ
description Introduction: Endoscopic third ventriculostomy is considered a safe and low-risk treatment of obstructive hydrocephalus. No systematic review has been conducted recently to establish benchmarks for success and complication rates. This knowledge gap makes it difficult to evaluate local institutional performance against international results. Research question: What are the results of endoscopic third ventriculostomy for obstructive hydrocephalus in the literature, and how does it compare to the results of our medium-sized neurosurgical center? Material and methods: We performed a retrospective case series of patients treated at the Department of Neurosurgery, Haukeland University Hospital, from January 1, 2013, to December 31, 2023. A systematic review was performed in accordance with the PRISMA guidelines. Results: Our case series consisted of 127 patients in a mixed-age cohort (mean: 37.3, range: 0–86) treated with endoscopic third ventriculostomy for hydrocephalus the last ten years. Previous shunting and neurosurgery were identified as risk factors for endoscopic third ventriculoscopy failure. In our systematic review, we found 64 reports with a total of 8409 patients eligible for inclusion. A higher success rate (78.7%) and complication rate (21.3%) were found in our patient material compared to the findings in our systematic review (respectively 73.4% and 11.6%). All complications in our material were transient and did not cause any permanent morbidity. Discussion and conclusions: Endoscopic third ventriculostomy has a favorable safety profile with high success rates in the treatment of obstructive hydrocephalus. Results from our systematic review can be used for internal audits at other neurosurgical centers.
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spelling doaj-art-e0fa801d5710422286dd2408a1ae0a4e2025-08-20T02:02:51ZengElsevierBrain and Spine2772-52942025-01-01510429110.1016/j.bas.2025.104291Complications and risk factors of endoscopic third ventriculostomy: A 10-year single-centre study and systematic literature reviewEinar Naveen Møen0Christian André Helland1Rupavathana Mahesparan2Department of Clinical Medicine, University of Bergen, Bergen, NorwayDepartment of Neurosurgery, Haukeland University Hospital, University of Bergen, Bergen, NorwayDepartment of Clinical Medicine, University of Bergen, Bergen, Norway; Department of Neurosurgery, Haukeland University Hospital, University of Bergen, Bergen, Norway; Corresponding author. Department of Clinical Medicine, University of Bergen, Bergen, Norway.Introduction: Endoscopic third ventriculostomy is considered a safe and low-risk treatment of obstructive hydrocephalus. No systematic review has been conducted recently to establish benchmarks for success and complication rates. This knowledge gap makes it difficult to evaluate local institutional performance against international results. Research question: What are the results of endoscopic third ventriculostomy for obstructive hydrocephalus in the literature, and how does it compare to the results of our medium-sized neurosurgical center? Material and methods: We performed a retrospective case series of patients treated at the Department of Neurosurgery, Haukeland University Hospital, from January 1, 2013, to December 31, 2023. A systematic review was performed in accordance with the PRISMA guidelines. Results: Our case series consisted of 127 patients in a mixed-age cohort (mean: 37.3, range: 0–86) treated with endoscopic third ventriculostomy for hydrocephalus the last ten years. Previous shunting and neurosurgery were identified as risk factors for endoscopic third ventriculoscopy failure. In our systematic review, we found 64 reports with a total of 8409 patients eligible for inclusion. A higher success rate (78.7%) and complication rate (21.3%) were found in our patient material compared to the findings in our systematic review (respectively 73.4% and 11.6%). All complications in our material were transient and did not cause any permanent morbidity. Discussion and conclusions: Endoscopic third ventriculostomy has a favorable safety profile with high success rates in the treatment of obstructive hydrocephalus. Results from our systematic review can be used for internal audits at other neurosurgical centers.http://www.sciencedirect.com/science/article/pii/S2772529425001109HydrocephalusEndoscopic third ventriculostomySurgical outcomesQuality assuranceSystematic reviewCase series
spellingShingle Einar Naveen Møen
Christian André Helland
Rupavathana Mahesparan
Complications and risk factors of endoscopic third ventriculostomy: A 10-year single-centre study and systematic literature review
Brain and Spine
Hydrocephalus
Endoscopic third ventriculostomy
Surgical outcomes
Quality assurance
Systematic review
Case series
title Complications and risk factors of endoscopic third ventriculostomy: A 10-year single-centre study and systematic literature review
title_full Complications and risk factors of endoscopic third ventriculostomy: A 10-year single-centre study and systematic literature review
title_fullStr Complications and risk factors of endoscopic third ventriculostomy: A 10-year single-centre study and systematic literature review
title_full_unstemmed Complications and risk factors of endoscopic third ventriculostomy: A 10-year single-centre study and systematic literature review
title_short Complications and risk factors of endoscopic third ventriculostomy: A 10-year single-centre study and systematic literature review
title_sort complications and risk factors of endoscopic third ventriculostomy a 10 year single centre study and systematic literature review
topic Hydrocephalus
Endoscopic third ventriculostomy
Surgical outcomes
Quality assurance
Systematic review
Case series
url http://www.sciencedirect.com/science/article/pii/S2772529425001109
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AT christianandrehelland complicationsandriskfactorsofendoscopicthirdventriculostomya10yearsinglecentrestudyandsystematicliteraturereview
AT rupavathanamahesparan complicationsandriskfactorsofendoscopicthirdventriculostomya10yearsinglecentrestudyandsystematicliteraturereview