Hamman’s syndrome in a patient with uncontrolled type 1 diabetes mellitus: a case report

Abstract Background Hamman’s syndrome is a clinical entity characterized by the spontaneous leakage of air into the mediastinum. We report a patient with Hamman’s syndrome associated with diabetes ketoacidosis (DKA). Case presentation A 20-year-old foreign technical intern visited to a hospital beca...

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Main Authors: Asahi Ishihara, Katsuyuki Sagishima, Tadashi Ejima, Manami Kuwahara, Naoyuki Hirata
Format: Article
Language:English
Published: SpringerOpen 2025-05-01
Series:JA Clinical Reports
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Online Access:https://doi.org/10.1186/s40981-025-00792-x
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author Asahi Ishihara
Katsuyuki Sagishima
Tadashi Ejima
Manami Kuwahara
Naoyuki Hirata
author_facet Asahi Ishihara
Katsuyuki Sagishima
Tadashi Ejima
Manami Kuwahara
Naoyuki Hirata
author_sort Asahi Ishihara
collection DOAJ
description Abstract Background Hamman’s syndrome is a clinical entity characterized by the spontaneous leakage of air into the mediastinum. We report a patient with Hamman’s syndrome associated with diabetes ketoacidosis (DKA). Case presentation A 20-year-old foreign technical intern visited to a hospital because of nausea and shortness of breath. He had been diagnosed with diabetes in his home country and had initiated insulin therapy; however, since arriving in Japan, he had not accessed any medical services. Computed tomography revealed pneumomediastinum, while laboratory tests showed marked hyperglycemia, metabolic acidosis, and a significantly elevated blood ketone level (15,044 µmol/L). The patient was diagnosed with Hamman’s syndrome associated with DKA. Upper gastrointestinal endoscopy showed no evidence of gastrointestinal perforation. Conservative intensive care, including insulin therapy and fluid resuscitation, resulted in clinical improvement. Conclusion This case highlights the importance of recognizing Hamman’s syndrome in DKA and the need for culturally competent care in international residents.
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spelling doaj-art-e0f9d54fc5874bc8a7e1fffddc07f6562025-08-20T02:32:07ZengSpringerOpenJA Clinical Reports2363-90242025-05-011111510.1186/s40981-025-00792-xHamman’s syndrome in a patient with uncontrolled type 1 diabetes mellitus: a case reportAsahi Ishihara0Katsuyuki Sagishima1Tadashi Ejima2Manami Kuwahara3Naoyuki Hirata4Department of Critical Care Medicine, Kumamoto University HospitalDepartment of Critical Care Medicine, Kumamoto University HospitalDepartment of Critical Care Medicine, Kumamoto University HospitalDepartment of Critical Care Medicine, Kumamoto University HospitalDepartment of Critical Care Medicine, Kumamoto University HospitalAbstract Background Hamman’s syndrome is a clinical entity characterized by the spontaneous leakage of air into the mediastinum. We report a patient with Hamman’s syndrome associated with diabetes ketoacidosis (DKA). Case presentation A 20-year-old foreign technical intern visited to a hospital because of nausea and shortness of breath. He had been diagnosed with diabetes in his home country and had initiated insulin therapy; however, since arriving in Japan, he had not accessed any medical services. Computed tomography revealed pneumomediastinum, while laboratory tests showed marked hyperglycemia, metabolic acidosis, and a significantly elevated blood ketone level (15,044 µmol/L). The patient was diagnosed with Hamman’s syndrome associated with DKA. Upper gastrointestinal endoscopy showed no evidence of gastrointestinal perforation. Conservative intensive care, including insulin therapy and fluid resuscitation, resulted in clinical improvement. Conclusion This case highlights the importance of recognizing Hamman’s syndrome in DKA and the need for culturally competent care in international residents.https://doi.org/10.1186/s40981-025-00792-xHamman’s syndromeDiabetic ketoacidosisPneumomediastinum
spellingShingle Asahi Ishihara
Katsuyuki Sagishima
Tadashi Ejima
Manami Kuwahara
Naoyuki Hirata
Hamman’s syndrome in a patient with uncontrolled type 1 diabetes mellitus: a case report
JA Clinical Reports
Hamman’s syndrome
Diabetic ketoacidosis
Pneumomediastinum
title Hamman’s syndrome in a patient with uncontrolled type 1 diabetes mellitus: a case report
title_full Hamman’s syndrome in a patient with uncontrolled type 1 diabetes mellitus: a case report
title_fullStr Hamman’s syndrome in a patient with uncontrolled type 1 diabetes mellitus: a case report
title_full_unstemmed Hamman’s syndrome in a patient with uncontrolled type 1 diabetes mellitus: a case report
title_short Hamman’s syndrome in a patient with uncontrolled type 1 diabetes mellitus: a case report
title_sort hamman s syndrome in a patient with uncontrolled type 1 diabetes mellitus a case report
topic Hamman’s syndrome
Diabetic ketoacidosis
Pneumomediastinum
url https://doi.org/10.1186/s40981-025-00792-x
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AT tadashiejima hammanssyndromeinapatientwithuncontrolledtype1diabetesmellitusacasereport
AT manamikuwahara hammanssyndromeinapatientwithuncontrolledtype1diabetesmellitusacasereport
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