Unmasking the Fungal Menace: A Case Report of Chronic Granulomatous Invasive Fungal Sinusitis of Maxilla
Chronic granulomatous invasive fungal sinusitis (CGIFS) is an uncommon type of invasive sinusitis that is characteristically seen in immunocompetent individuals. Common clinical manifestations of this condition include proptosis, cheek swelling, and headache. The pathogenic organism is <i>Aspe...
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MDPI AG
2025-02-01
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| Series: | Sinusitis |
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| author | Swathi Krishna Vivekanand Ashok Shahseena Abdulla Rosmy John Prathap Ramalingam |
| author_facet | Swathi Krishna Vivekanand Ashok Shahseena Abdulla Rosmy John Prathap Ramalingam |
| author_sort | Swathi Krishna |
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| description | Chronic granulomatous invasive fungal sinusitis (CGIFS) is an uncommon type of invasive sinusitis that is characteristically seen in immunocompetent individuals. Common clinical manifestations of this condition include proptosis, cheek swelling, and headache. The pathogenic organism is <i>Aspergillus</i> in the majority of reported cases. Diagnosis is made by histopathological and microbiological examination of tissue specimens. Due to its expansible nature, bone erosion is also associated with this condition. Treatment is surgical clearance/debulking followed by long-term antifungal therapy. Here, we report the case of a 31-year-old male presented with right-side cheek swelling. The patient underwent a medial maxillectomy and was diagnosed with CGIFS. The patient was put on oral voriconazole for 3 months. To conclude, CGIFS is a rare variant of invasive fungal sinusitis that may mimic malignancy or granulomatous diseases such as tuberculosis, rhinoscleroma, and syphilis. Accurate diagnosis is of utmost importance in providing management for CGIFS. |
| format | Article |
| id | doaj-art-e0ee14ca691b4bbaaca286c319ec1874 |
| institution | Kabale University |
| issn | 2673-351X |
| language | English |
| publishDate | 2025-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Sinusitis |
| spelling | doaj-art-e0ee14ca691b4bbaaca286c319ec18742025-08-20T03:26:52ZengMDPI AGSinusitis2673-351X2025-02-0191410.3390/sinusitis9010004Unmasking the Fungal Menace: A Case Report of Chronic Granulomatous Invasive Fungal Sinusitis of MaxillaSwathi Krishna0Vivekanand Ashok1Shahseena Abdulla2Rosmy John3Prathap Ramalingam4Department of Otolaryngology and Head and Neck Surgery, Karuna Medical College, Palakkad 678103, Kerala, IndiaDepartment of Otolaryngology and Head and Neck Surgery, Karuna Medical College, Palakkad 678103, Kerala, IndiaDepartment of Pathology, Karuna Medical College, Palakkad 678103, Kerala, IndiaDepartment of Pathology, Karuna Medical College, Palakkad 678103, Kerala, IndiaDepartment of Otolaryngology and Head and Neck Surgery, Karuna Medical College, Palakkad 678103, Kerala, IndiaChronic granulomatous invasive fungal sinusitis (CGIFS) is an uncommon type of invasive sinusitis that is characteristically seen in immunocompetent individuals. Common clinical manifestations of this condition include proptosis, cheek swelling, and headache. The pathogenic organism is <i>Aspergillus</i> in the majority of reported cases. Diagnosis is made by histopathological and microbiological examination of tissue specimens. Due to its expansible nature, bone erosion is also associated with this condition. Treatment is surgical clearance/debulking followed by long-term antifungal therapy. Here, we report the case of a 31-year-old male presented with right-side cheek swelling. The patient underwent a medial maxillectomy and was diagnosed with CGIFS. The patient was put on oral voriconazole for 3 months. To conclude, CGIFS is a rare variant of invasive fungal sinusitis that may mimic malignancy or granulomatous diseases such as tuberculosis, rhinoscleroma, and syphilis. Accurate diagnosis is of utmost importance in providing management for CGIFS.https://www.mdpi.com/2673-351X/9/1/4invasive fungal sinusitisgranulomatous fungal sinusitis<i>Aspergillus</i> |
| spellingShingle | Swathi Krishna Vivekanand Ashok Shahseena Abdulla Rosmy John Prathap Ramalingam Unmasking the Fungal Menace: A Case Report of Chronic Granulomatous Invasive Fungal Sinusitis of Maxilla Sinusitis invasive fungal sinusitis granulomatous fungal sinusitis <i>Aspergillus</i> |
| title | Unmasking the Fungal Menace: A Case Report of Chronic Granulomatous Invasive Fungal Sinusitis of Maxilla |
| title_full | Unmasking the Fungal Menace: A Case Report of Chronic Granulomatous Invasive Fungal Sinusitis of Maxilla |
| title_fullStr | Unmasking the Fungal Menace: A Case Report of Chronic Granulomatous Invasive Fungal Sinusitis of Maxilla |
| title_full_unstemmed | Unmasking the Fungal Menace: A Case Report of Chronic Granulomatous Invasive Fungal Sinusitis of Maxilla |
| title_short | Unmasking the Fungal Menace: A Case Report of Chronic Granulomatous Invasive Fungal Sinusitis of Maxilla |
| title_sort | unmasking the fungal menace a case report of chronic granulomatous invasive fungal sinusitis of maxilla |
| topic | invasive fungal sinusitis granulomatous fungal sinusitis <i>Aspergillus</i> |
| url | https://www.mdpi.com/2673-351X/9/1/4 |
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