Diffuse large B-cell type of the primary non-Hodgkin´s lymphoma of the liver: A diagnostic problem

Introduction. Primary Non-Hodgkin lymphoma of the liver is an extremely rare disease. It most often occurs as a diffuse large B-cell type. Case outline. We present the case of a 75-year-old patient who was admitted to our clinic with rightsided subcostal pain accompanied by malaise, weakness, and el...

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Main Authors: Basarić Dragan, Milošević Stefan, Lekić Nebojša, Šaponjski Dušan, Mitrović-Jovanović Milica
Format: Article
Language:English
Published: Serbian Medical Society 2025-01-01
Series:Srpski Arhiv za Celokupno Lekarstvo
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Online Access:https://doiserbia.nb.rs/img/doi/0370-8179/2025/0370-81792400096B.pdf
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author Basarić Dragan
Milošević Stefan
Lekić Nebojša
Šaponjski Dušan
Mitrović-Jovanović Milica
author_facet Basarić Dragan
Milošević Stefan
Lekić Nebojša
Šaponjski Dušan
Mitrović-Jovanović Milica
author_sort Basarić Dragan
collection DOAJ
description Introduction. Primary Non-Hodgkin lymphoma of the liver is an extremely rare disease. It most often occurs as a diffuse large B-cell type. Case outline. We present the case of a 75-year-old patient who was admitted to our clinic with rightsided subcostal pain accompanied by malaise, weakness, and elevated body temperature. Laboratory analyzes were within normal limits. Ultrasonography and computed tomography findings showed a sharply marginated inhomogeneous lesion in the right liver lobe with central necrosis. Intraoperatively and pathohistologically, it was confirmed that it was diffuse large B-cell lymphoma of the liver. Surgery, chemotherapy, radiotherapy and their combination are the methods of treatment. Conclusion. Surgical treatment with chemotherapy allows for a significantly higher survival rate.
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series Srpski Arhiv za Celokupno Lekarstvo
spelling doaj-art-e0ed119dd5e84bf7ad771ff60589305c2025-08-20T02:56:22ZengSerbian Medical SocietySrpski Arhiv za Celokupno Lekarstvo0370-81792406-08952025-01-011531-2939610.2298/SARH240727096B0370-81792400096BDiffuse large B-cell type of the primary non-Hodgkin´s lymphoma of the liver: A diagnostic problemBasarić Dragan0Milošević Stefan1Lekić Nebojša2Šaponjski Dušan3https://orcid.org/0000-0002-6640-234XMitrović-Jovanović Milica4https://orcid.org/0000-0002-7525-7615University Clinical Center of Serbia, Clinic for Digestive Surgery, Belgrade, Serbia + University of Belgrade, Faculty of Medicine, Belgrade, SerbiaUniversity Clinical Center of Serbia, Center of Radiology, Belgrade, SerbiaUniversity Clinical Center of Serbia, Clinic for Digestive Surgery, Belgrade, Serbia + University of Belgrade, Faculty of Medicine, Belgrade, SerbiaUniversity of Belgrade, Faculty of Medicine, Belgrade, Serbia + University Clinical Center of Serbia, Center of Radiology, Belgrade, SerbiaUniversity of Belgrade, Faculty of Medicine, Belgrade, Serbia + University Clinical Center of Serbia, Center of Radiology, Belgrade, SerbiaIntroduction. Primary Non-Hodgkin lymphoma of the liver is an extremely rare disease. It most often occurs as a diffuse large B-cell type. Case outline. We present the case of a 75-year-old patient who was admitted to our clinic with rightsided subcostal pain accompanied by malaise, weakness, and elevated body temperature. Laboratory analyzes were within normal limits. Ultrasonography and computed tomography findings showed a sharply marginated inhomogeneous lesion in the right liver lobe with central necrosis. Intraoperatively and pathohistologically, it was confirmed that it was diffuse large B-cell lymphoma of the liver. Surgery, chemotherapy, radiotherapy and their combination are the methods of treatment. Conclusion. Surgical treatment with chemotherapy allows for a significantly higher survival rate.https://doiserbia.nb.rs/img/doi/0370-8179/2025/0370-81792400096B.pdfnon-hodgkin lymphomaliverdiagnosistreatment
spellingShingle Basarić Dragan
Milošević Stefan
Lekić Nebojša
Šaponjski Dušan
Mitrović-Jovanović Milica
Diffuse large B-cell type of the primary non-Hodgkin´s lymphoma of the liver: A diagnostic problem
Srpski Arhiv za Celokupno Lekarstvo
non-hodgkin lymphoma
liver
diagnosis
treatment
title Diffuse large B-cell type of the primary non-Hodgkin´s lymphoma of the liver: A diagnostic problem
title_full Diffuse large B-cell type of the primary non-Hodgkin´s lymphoma of the liver: A diagnostic problem
title_fullStr Diffuse large B-cell type of the primary non-Hodgkin´s lymphoma of the liver: A diagnostic problem
title_full_unstemmed Diffuse large B-cell type of the primary non-Hodgkin´s lymphoma of the liver: A diagnostic problem
title_short Diffuse large B-cell type of the primary non-Hodgkin´s lymphoma of the liver: A diagnostic problem
title_sort diffuse large b cell type of the primary non hodgkin´s lymphoma of the liver a diagnostic problem
topic non-hodgkin lymphoma
liver
diagnosis
treatment
url https://doiserbia.nb.rs/img/doi/0370-8179/2025/0370-81792400096B.pdf
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AT lekicnebojsa diffuselargebcelltypeoftheprimarynonhodgkinslymphomaoftheliveradiagnosticproblem
AT saponjskidusan diffuselargebcelltypeoftheprimarynonhodgkinslymphomaoftheliveradiagnosticproblem
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