High-Resolution Optical Coherence Tomography Retinal Imaging: A Case Series Illustrating Potential and Limitations

Purpose. To present a series of retinal disease cases that were imaged by spectral domain optical coherence tomography (SD-OCT) in order to illustrate the potential and limitations of this new imaging modality. Methods. The series comprised four selected cases (one case each) of age-related macular...

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Main Authors: Olena Puzyeyeva, Wai Ching Lam, John G. Flanagan, Michael H. Brent, Robert G. Devenyi, Mark S. Mandelcorn, Tien Wong, Christopher Hudson
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Journal of Ophthalmology
Online Access:http://dx.doi.org/10.1155/2011/764183
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author Olena Puzyeyeva
Wai Ching Lam
John G. Flanagan
Michael H. Brent
Robert G. Devenyi
Mark S. Mandelcorn
Tien Wong
Christopher Hudson
author_facet Olena Puzyeyeva
Wai Ching Lam
John G. Flanagan
Michael H. Brent
Robert G. Devenyi
Mark S. Mandelcorn
Tien Wong
Christopher Hudson
author_sort Olena Puzyeyeva
collection DOAJ
description Purpose. To present a series of retinal disease cases that were imaged by spectral domain optical coherence tomography (SD-OCT) in order to illustrate the potential and limitations of this new imaging modality. Methods. The series comprised four selected cases (one case each) of age-related macular degeneration (ARMD), diabetic retinopathy (DR), central retinal artery occlusion (CRAO), and branch retinal vein occlusion (BRVO). Patients were imaged using the Heidelberg Spectralis (Heidelberg Engineering, Germany) in SD-OCT mode. Patients also underwent digital fundus photography and clinical assessment. Results. SD-OCT imaging of a case of age-related macular degeneration revealed a subfoveal choroidal neovascular membrane with detachment of the retinal pigment epithelium (RPE) and neurosensory retina. Using SD-OCT, the cases of DR and BRVO both exhibited macular edema with cystoid spaces visible in the outer retina. Conclusions. The ability of SD-OCT to clearly and objectively elucidate subtle morphological changes within the retinal layers provides information that can be used to formulate diagnoses with greater confidence.
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institution Kabale University
issn 2090-004X
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language English
publishDate 2011-01-01
publisher Wiley
record_format Article
series Journal of Ophthalmology
spelling doaj-art-e0dfdc6f01b6467c8b9902d1fe9511802025-02-03T06:08:04ZengWileyJournal of Ophthalmology2090-004X2090-00582011-01-01201110.1155/2011/764183764183High-Resolution Optical Coherence Tomography Retinal Imaging: A Case Series Illustrating Potential and LimitationsOlena Puzyeyeva0Wai Ching Lam1John G. Flanagan2Michael H. Brent3Robert G. Devenyi4Mark S. Mandelcorn5Tien Wong6Christopher Hudson7Retina Research Group, Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, ON, M5T 2S8, CanadaRetina Research Group, Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, ON, M5T 2S8, CanadaRetina Research Group, Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, ON, M5T 2S8, CanadaRetina Research Group, Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, ON, M5T 2S8, CanadaRetina Research Group, Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, ON, M5T 2S8, CanadaRetina Research Group, Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, ON, M5T 2S8, CanadaRetina Research Group, Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, ON, M5T 2S8, CanadaRetina Research Group, Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, ON, M5T 2S8, CanadaPurpose. To present a series of retinal disease cases that were imaged by spectral domain optical coherence tomography (SD-OCT) in order to illustrate the potential and limitations of this new imaging modality. Methods. The series comprised four selected cases (one case each) of age-related macular degeneration (ARMD), diabetic retinopathy (DR), central retinal artery occlusion (CRAO), and branch retinal vein occlusion (BRVO). Patients were imaged using the Heidelberg Spectralis (Heidelberg Engineering, Germany) in SD-OCT mode. Patients also underwent digital fundus photography and clinical assessment. Results. SD-OCT imaging of a case of age-related macular degeneration revealed a subfoveal choroidal neovascular membrane with detachment of the retinal pigment epithelium (RPE) and neurosensory retina. Using SD-OCT, the cases of DR and BRVO both exhibited macular edema with cystoid spaces visible in the outer retina. Conclusions. The ability of SD-OCT to clearly and objectively elucidate subtle morphological changes within the retinal layers provides information that can be used to formulate diagnoses with greater confidence.http://dx.doi.org/10.1155/2011/764183
spellingShingle Olena Puzyeyeva
Wai Ching Lam
John G. Flanagan
Michael H. Brent
Robert G. Devenyi
Mark S. Mandelcorn
Tien Wong
Christopher Hudson
High-Resolution Optical Coherence Tomography Retinal Imaging: A Case Series Illustrating Potential and Limitations
Journal of Ophthalmology
title High-Resolution Optical Coherence Tomography Retinal Imaging: A Case Series Illustrating Potential and Limitations
title_full High-Resolution Optical Coherence Tomography Retinal Imaging: A Case Series Illustrating Potential and Limitations
title_fullStr High-Resolution Optical Coherence Tomography Retinal Imaging: A Case Series Illustrating Potential and Limitations
title_full_unstemmed High-Resolution Optical Coherence Tomography Retinal Imaging: A Case Series Illustrating Potential and Limitations
title_short High-Resolution Optical Coherence Tomography Retinal Imaging: A Case Series Illustrating Potential and Limitations
title_sort high resolution optical coherence tomography retinal imaging a case series illustrating potential and limitations
url http://dx.doi.org/10.1155/2011/764183
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