Septic pulmonary embolism at a tertiary care hospital in Bahrain: clinical features and treatment outcomes
Introduction Septic pulmonary embolism (SPE) is a type of nonthrombotic pulmonary embolism that poses a clinical challenge due to its rarity of occurrence, varied presentation, and need for distinctive diagnostic and management options. It accounts for less than 3% of pulmonary embolisms. Despite it...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2025-04-01
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| Series: | Egyptian Journal of Chest Disease and Tuberculosis |
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| Online Access: | https://doi.org/10.4103/ecdt.ecdt_71_24 |
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| author | Amit Panjwani Husain Kadhem Subhi Isa Akleh Jalila Sayed Mohamed Sornali Roy Layal Omaruddin |
| author_facet | Amit Panjwani Husain Kadhem Subhi Isa Akleh Jalila Sayed Mohamed Sornali Roy Layal Omaruddin |
| author_sort | Amit Panjwani |
| collection | DOAJ |
| description | Introduction Septic pulmonary embolism (SPE) is a type of nonthrombotic pulmonary embolism that poses a clinical challenge due to its rarity of occurrence, varied presentation, and need for distinctive diagnostic and management options. It accounts for less than 3% of pulmonary embolisms. Despite its fatal potential, there is a paucity of data on patients with SPE in the Kingdom of Bahrain, and is limited to case reports. Aims and objectives This study was undertaken to illustrate the clinical, microbiological, and radiological features of patients with SPE and to understand treatment outcomes in this rare cohort of patients from this island nation. Methods We retrospectively analyzed 12 patients of SPE encountered in an academic tertiary care referral hospital over 4 years. Results There was male preponderance with more than two-thirds of patients admitted in the intensive care unit. Staphylococcus aureus was isolated in 66.7% of cases. Bilateral nodules in peripheral location were the most encountered radiological abnormality. Most of these nodules had a feeding vessel sign (92%) and cavitation. Infectious vegetations from the right side of the heart were detected in 42% of cases. All patients received parenteral antibiotic therapy while drainage at extrapulmonary sites was done in 50% of cases. The overall survival rate was 75% across the study subjects. Elevated creatinine levels and deranged INR were associated with an increased risk of in-hospital mortality. Conclusion Staphylococcus aureus is the most common culprit in patients of SPE. Prompt initiation of appropriate antimicrobial therapy along with surgical intervention, where indicated, helps in achieving a favorable outcome after treatment of SPE. |
| format | Article |
| id | doaj-art-e0d59cc3e1ae4fc78b5e84f6095fcc99 |
| institution | Kabale University |
| issn | 0422-7638 2090-9950 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Egyptian Journal of Chest Disease and Tuberculosis |
| spelling | doaj-art-e0d59cc3e1ae4fc78b5e84f6095fcc992025-08-20T03:49:46ZengWolters Kluwer Medknow PublicationsEgyptian Journal of Chest Disease and Tuberculosis0422-76382090-99502025-04-0174224725310.4103/ecdt.ecdt_71_24Septic pulmonary embolism at a tertiary care hospital in Bahrain: clinical features and treatment outcomesAmit PanjwaniHusain KadhemSubhi Isa AklehJalila Sayed MohamedSornali RoyLayal OmaruddinIntroduction Septic pulmonary embolism (SPE) is a type of nonthrombotic pulmonary embolism that poses a clinical challenge due to its rarity of occurrence, varied presentation, and need for distinctive diagnostic and management options. It accounts for less than 3% of pulmonary embolisms. Despite its fatal potential, there is a paucity of data on patients with SPE in the Kingdom of Bahrain, and is limited to case reports. Aims and objectives This study was undertaken to illustrate the clinical, microbiological, and radiological features of patients with SPE and to understand treatment outcomes in this rare cohort of patients from this island nation. Methods We retrospectively analyzed 12 patients of SPE encountered in an academic tertiary care referral hospital over 4 years. Results There was male preponderance with more than two-thirds of patients admitted in the intensive care unit. Staphylococcus aureus was isolated in 66.7% of cases. Bilateral nodules in peripheral location were the most encountered radiological abnormality. Most of these nodules had a feeding vessel sign (92%) and cavitation. Infectious vegetations from the right side of the heart were detected in 42% of cases. All patients received parenteral antibiotic therapy while drainage at extrapulmonary sites was done in 50% of cases. The overall survival rate was 75% across the study subjects. Elevated creatinine levels and deranged INR were associated with an increased risk of in-hospital mortality. Conclusion Staphylococcus aureus is the most common culprit in patients of SPE. Prompt initiation of appropriate antimicrobial therapy along with surgical intervention, where indicated, helps in achieving a favorable outcome after treatment of SPE.https://doi.org/10.4103/ecdt.ecdt_71_24computed tomographyechocardiographyfeeding vessel signseptic pulmonary embolismstaphylococcus |
| spellingShingle | Amit Panjwani Husain Kadhem Subhi Isa Akleh Jalila Sayed Mohamed Sornali Roy Layal Omaruddin Septic pulmonary embolism at a tertiary care hospital in Bahrain: clinical features and treatment outcomes Egyptian Journal of Chest Disease and Tuberculosis computed tomography echocardiography feeding vessel sign septic pulmonary embolism staphylococcus |
| title | Septic pulmonary embolism at a tertiary care hospital in Bahrain: clinical features and treatment outcomes |
| title_full | Septic pulmonary embolism at a tertiary care hospital in Bahrain: clinical features and treatment outcomes |
| title_fullStr | Septic pulmonary embolism at a tertiary care hospital in Bahrain: clinical features and treatment outcomes |
| title_full_unstemmed | Septic pulmonary embolism at a tertiary care hospital in Bahrain: clinical features and treatment outcomes |
| title_short | Septic pulmonary embolism at a tertiary care hospital in Bahrain: clinical features and treatment outcomes |
| title_sort | septic pulmonary embolism at a tertiary care hospital in bahrain clinical features and treatment outcomes |
| topic | computed tomography echocardiography feeding vessel sign septic pulmonary embolism staphylococcus |
| url | https://doi.org/10.4103/ecdt.ecdt_71_24 |
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