Absence of gut microbiota restoration following meropenem treatment in a systemic infection model

Absence of gut microbiota restoration following meropenem treatment in a systemic infection model

Abstract Antibiotics have been shown to have unintended effects on the host by disrupting the beneficial microbiota. In this study, we explored and longitudinally monitored microbiota during and after antibiotic treatment for infection. We induced a systemic Escherichia coli infection in 45 BALB/c m...

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Main Authors: Filipe Moura Ribeiro, Camila Fontoura Acosta Ribeiro, Elizabete de Souza Cândido, Danieli Fernanda Buccini, Marlon Henrique Cardoso, Gislaine Greice de Oliveira Silva Silveira, Carolina Moura de Souza, Osmar Nascimento Silva, Gisele Braziliano de Andrade, Alanderson Rodrigues da Silva, Franciele Bathel da Mota, Sarah Saory Makimoto, Rosangela dos Santos Ferreira, Nathália Cavichiolli de Oliveira, Alinne Pereira de Castro, Cristiano Marcelo Espínola Carvalho, Cesar de la Fuente-Nunez, Octávio Luiz Franco
Format: Article
Language:English
Published: Nature Portfolio 2025-06-01
Series:npj Antimicrobials and Resistance
Online Access:https://doi.org/10.1038/s44259-025-00129-9
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