USE OF INHALATION ANESTHETICS DURING CARDIOPULMONARY BYPASS

Protection of myocardium from ischemic and reperfusion lesions continues to be an important issue in the modern cardiac surgery. Russian and foreign publications contain a significant number of data about the protective impact of pre- and post-conditioning with inhalation anesthetics (sevoflurane, i...

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Main Authors: E. Yu. Chepurnyak, A. V. Panov, L. S. Lokshin
Format: Article
Language:Russian
Published: New Terra Publishing House 2018-08-01
Series:Вестник анестезиологии и реаниматологии
Subjects:
Online Access:https://www.vair-journal.com/jour/article/view/270
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author E. Yu. Chepurnyak
A. V. Panov
L. S. Lokshin
author_facet E. Yu. Chepurnyak
A. V. Panov
L. S. Lokshin
author_sort E. Yu. Chepurnyak
collection DOAJ
description Protection of myocardium from ischemic and reperfusion lesions continues to be an important issue in the modern cardiac surgery. Russian and foreign publications contain a significant number of data about the protective impact of pre- and post-conditioning with inhalation anesthetics (sevoflurane, isoflurane, and desflurane) on the myocardium. The article highlights that this protective action is maximum when these drugs are used during the whole operation and it means during cardiopulmonary bypass as well. Therefore, currently, the listed above inhalation anesthetics are used fairly frequent during cardiopulmonary bypass. However, the technology of inhalation anesthesia during perfusion has a number of specific features: changes in the pharmacokinetics of drugs (which provides impact on the dosing of anesthetics), design of oxygenator, which plays a certain role when the anesthetics are supplied to the blood, monitoring during inhalation anesthesia, technical assistance for this technology and important safety issues. This review describes the above-mentioned aspects.
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institution Kabale University
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series Вестник анестезиологии и реаниматологии
spelling doaj-art-e0c3409f93ec40a88837c70bbfc965bf2025-08-20T03:42:47ZrusNew Terra Publishing HouseВестник анестезиологии и реаниматологии2078-56582541-86532018-08-01154707510.21292/2078-5658-2018-15-4-70-75258USE OF INHALATION ANESTHETICS DURING CARDIOPULMONARY BYPASSE. Yu. Chepurnyak0A. V. Panov1L. S. Lokshin2B.V. Petrovsky Russian Research Surgery Center.B.V. Petrovsky Russian Research Surgery Center.B.V. Petrovsky Russian Research Surgery Center.Protection of myocardium from ischemic and reperfusion lesions continues to be an important issue in the modern cardiac surgery. Russian and foreign publications contain a significant number of data about the protective impact of pre- and post-conditioning with inhalation anesthetics (sevoflurane, isoflurane, and desflurane) on the myocardium. The article highlights that this protective action is maximum when these drugs are used during the whole operation and it means during cardiopulmonary bypass as well. Therefore, currently, the listed above inhalation anesthetics are used fairly frequent during cardiopulmonary bypass. However, the technology of inhalation anesthesia during perfusion has a number of specific features: changes in the pharmacokinetics of drugs (which provides impact on the dosing of anesthetics), design of oxygenator, which plays a certain role when the anesthetics are supplied to the blood, monitoring during inhalation anesthesia, technical assistance for this technology and important safety issues. This review describes the above-mentioned aspects.https://www.vair-journal.com/jour/article/view/270inhalation anestheticscardiopulmonary bypasscardiac surgery
spellingShingle E. Yu. Chepurnyak
A. V. Panov
L. S. Lokshin
USE OF INHALATION ANESTHETICS DURING CARDIOPULMONARY BYPASS
Вестник анестезиологии и реаниматологии
inhalation anesthetics
cardiopulmonary bypass
cardiac surgery
title USE OF INHALATION ANESTHETICS DURING CARDIOPULMONARY BYPASS
title_full USE OF INHALATION ANESTHETICS DURING CARDIOPULMONARY BYPASS
title_fullStr USE OF INHALATION ANESTHETICS DURING CARDIOPULMONARY BYPASS
title_full_unstemmed USE OF INHALATION ANESTHETICS DURING CARDIOPULMONARY BYPASS
title_short USE OF INHALATION ANESTHETICS DURING CARDIOPULMONARY BYPASS
title_sort use of inhalation anesthetics during cardiopulmonary bypass
topic inhalation anesthetics
cardiopulmonary bypass
cardiac surgery
url https://www.vair-journal.com/jour/article/view/270
work_keys_str_mv AT eyuchepurnyak useofinhalationanestheticsduringcardiopulmonarybypass
AT avpanov useofinhalationanestheticsduringcardiopulmonarybypass
AT lslokshin useofinhalationanestheticsduringcardiopulmonarybypass