Research Progress on the Chemical Constituents and Pharmacological Effects of <i>Houttuynia cordata</i> Thunb and a Predictive Analysis of Quality Markers
<i>Houttuynia cordata</i> (<i>H. cordata</i>) is widely used in respiratory disease control as an important heat-clearing and detoxifying traditional Chinese medicine. It effectively clears away heat and toxins, eliminates carbuncles, and drains pus, and it is diuretic and de...
Saved in:
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2024-12-01
|
| Series: | Current Issues in Molecular Biology |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1467-3045/47/1/18 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832588803810787328 |
|---|---|
| author | Zhuo Yang Peng Ji Chenchen Li Fanlin Wu Yongli Hua Yanming Wei Yuxia Cao |
| author_facet | Zhuo Yang Peng Ji Chenchen Li Fanlin Wu Yongli Hua Yanming Wei Yuxia Cao |
| author_sort | Zhuo Yang |
| collection | DOAJ |
| description | <i>Houttuynia cordata</i> (<i>H. cordata</i>) is widely used in respiratory disease control as an important heat-clearing and detoxifying traditional Chinese medicine. It effectively clears away heat and toxins, eliminates carbuncles, and drains pus, and it is diuretic and detoxicating. The aim of this study is to review the botany, chemical composition, pharmacological effects, and quality control of <i>H. cordata</i> to establish a better-quality evaluation system. Google Scholar, Baidu Scholar, PubMed, ScienceDirect, Web of Science, and multiple databases, including China National Knowledge Infrastructure (CNKI) and Wanfang Data, were searched. A structural diagram of the compound was drawn using ChemDraw software. <i>H. cordata</i> contains volatile oils, flavonoids, and alkaloids. It has antibacterial, anti-inflammatory, antiviral, antioxidant, antitumor, and immunity-enhancing pharmacological effects. By analyzing the literature, it was predicted that Houttuynia sodium, methyl nonyl ketone, quercetin, and quercitrin could be used as the quality markers (Q-marker) of <i>H. cordata</i>. This provides a basis for further research into the applications of <i>H. cordata</i>. |
| format | Article |
| id | doaj-art-e0bb64c3dfe34f3e99a8aefb7c8fb71a |
| institution | Kabale University |
| issn | 1467-3037 1467-3045 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Current Issues in Molecular Biology |
| spelling | doaj-art-e0bb64c3dfe34f3e99a8aefb7c8fb71a2025-01-24T13:27:25ZengMDPI AGCurrent Issues in Molecular Biology1467-30371467-30452024-12-014711810.3390/cimb47010018Research Progress on the Chemical Constituents and Pharmacological Effects of <i>Houttuynia cordata</i> Thunb and a Predictive Analysis of Quality MarkersZhuo Yang0Peng Ji1Chenchen Li2Fanlin Wu3Yongli Hua4Yanming Wei5Yuxia Cao6College of Veterinary Medicine, Gansu Agricultural University, Lanzhou 730070, ChinaCollege of Veterinary Medicine, Gansu Agricultural University, Lanzhou 730070, ChinaCollege of Veterinary Medicine, Gansu Agricultural University, Lanzhou 730070, ChinaLanzhou Institute of Husbandry and Pharmaceutical Science, Chinese Academy of Agricultural Science, Lanzhou 730070, ChinaCollege of Veterinary Medicine, Gansu Agricultural University, Lanzhou 730070, ChinaCollege of Veterinary Medicine, Gansu Agricultural University, Lanzhou 730070, ChinaCollege of Veterinary Medicine, Gansu Agricultural University, Lanzhou 730070, China<i>Houttuynia cordata</i> (<i>H. cordata</i>) is widely used in respiratory disease control as an important heat-clearing and detoxifying traditional Chinese medicine. It effectively clears away heat and toxins, eliminates carbuncles, and drains pus, and it is diuretic and detoxicating. The aim of this study is to review the botany, chemical composition, pharmacological effects, and quality control of <i>H. cordata</i> to establish a better-quality evaluation system. Google Scholar, Baidu Scholar, PubMed, ScienceDirect, Web of Science, and multiple databases, including China National Knowledge Infrastructure (CNKI) and Wanfang Data, were searched. A structural diagram of the compound was drawn using ChemDraw software. <i>H. cordata</i> contains volatile oils, flavonoids, and alkaloids. It has antibacterial, anti-inflammatory, antiviral, antioxidant, antitumor, and immunity-enhancing pharmacological effects. By analyzing the literature, it was predicted that Houttuynia sodium, methyl nonyl ketone, quercetin, and quercitrin could be used as the quality markers (Q-marker) of <i>H. cordata</i>. This provides a basis for further research into the applications of <i>H. cordata</i>.https://www.mdpi.com/1467-3045/47/1/18<i>H. cordata</i>chemical constituentspharmacological actionquality markerresearch progress |
| spellingShingle | Zhuo Yang Peng Ji Chenchen Li Fanlin Wu Yongli Hua Yanming Wei Yuxia Cao Research Progress on the Chemical Constituents and Pharmacological Effects of <i>Houttuynia cordata</i> Thunb and a Predictive Analysis of Quality Markers Current Issues in Molecular Biology <i>H. cordata</i> chemical constituents pharmacological action quality marker research progress |
| title | Research Progress on the Chemical Constituents and Pharmacological Effects of <i>Houttuynia cordata</i> Thunb and a Predictive Analysis of Quality Markers |
| title_full | Research Progress on the Chemical Constituents and Pharmacological Effects of <i>Houttuynia cordata</i> Thunb and a Predictive Analysis of Quality Markers |
| title_fullStr | Research Progress on the Chemical Constituents and Pharmacological Effects of <i>Houttuynia cordata</i> Thunb and a Predictive Analysis of Quality Markers |
| title_full_unstemmed | Research Progress on the Chemical Constituents and Pharmacological Effects of <i>Houttuynia cordata</i> Thunb and a Predictive Analysis of Quality Markers |
| title_short | Research Progress on the Chemical Constituents and Pharmacological Effects of <i>Houttuynia cordata</i> Thunb and a Predictive Analysis of Quality Markers |
| title_sort | research progress on the chemical constituents and pharmacological effects of i houttuynia cordata i thunb and a predictive analysis of quality markers |
| topic | <i>H. cordata</i> chemical constituents pharmacological action quality marker research progress |
| url | https://www.mdpi.com/1467-3045/47/1/18 |
| work_keys_str_mv | AT zhuoyang researchprogressonthechemicalconstituentsandpharmacologicaleffectsofihouttuyniacordataithunbandapredictiveanalysisofqualitymarkers AT pengji researchprogressonthechemicalconstituentsandpharmacologicaleffectsofihouttuyniacordataithunbandapredictiveanalysisofqualitymarkers AT chenchenli researchprogressonthechemicalconstituentsandpharmacologicaleffectsofihouttuyniacordataithunbandapredictiveanalysisofqualitymarkers AT fanlinwu researchprogressonthechemicalconstituentsandpharmacologicaleffectsofihouttuyniacordataithunbandapredictiveanalysisofqualitymarkers AT yonglihua researchprogressonthechemicalconstituentsandpharmacologicaleffectsofihouttuyniacordataithunbandapredictiveanalysisofqualitymarkers AT yanmingwei researchprogressonthechemicalconstituentsandpharmacologicaleffectsofihouttuyniacordataithunbandapredictiveanalysisofqualitymarkers AT yuxiacao researchprogressonthechemicalconstituentsandpharmacologicaleffectsofihouttuyniacordataithunbandapredictiveanalysisofqualitymarkers |