Research Progress on the Chemical Constituents and Pharmacological Effects of <i>Houttuynia cordata</i> Thunb and a Predictive Analysis of Quality Markers

<i>Houttuynia cordata</i> (<i>H. cordata</i>) is widely used in respiratory disease control as an important heat-clearing and detoxifying traditional Chinese medicine. It effectively clears away heat and toxins, eliminates carbuncles, and drains pus, and it is diuretic and de...

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Bibliographic Details
Main Authors: Zhuo Yang, Peng Ji, Chenchen Li, Fanlin Wu, Yongli Hua, Yanming Wei, Yuxia Cao
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Current Issues in Molecular Biology
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Online Access:https://www.mdpi.com/1467-3045/47/1/18
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Summary:<i>Houttuynia cordata</i> (<i>H. cordata</i>) is widely used in respiratory disease control as an important heat-clearing and detoxifying traditional Chinese medicine. It effectively clears away heat and toxins, eliminates carbuncles, and drains pus, and it is diuretic and detoxicating. The aim of this study is to review the botany, chemical composition, pharmacological effects, and quality control of <i>H. cordata</i> to establish a better-quality evaluation system. Google Scholar, Baidu Scholar, PubMed, ScienceDirect, Web of Science, and multiple databases, including China National Knowledge Infrastructure (CNKI) and Wanfang Data, were searched. A structural diagram of the compound was drawn using ChemDraw software. <i>H. cordata</i> contains volatile oils, flavonoids, and alkaloids. It has antibacterial, anti-inflammatory, antiviral, antioxidant, antitumor, and immunity-enhancing pharmacological effects. By analyzing the literature, it was predicted that Houttuynia sodium, methyl nonyl ketone, quercetin, and quercitrin could be used as the quality markers (Q-marker) of <i>H. cordata</i>. This provides a basis for further research into the applications of <i>H. cordata</i>.
ISSN:1467-3037
1467-3045