The development of universal alopecia during therapy with TNF-α inhibitors in patients with ankylosing spondylitis: description of three cases
Alopecia areata (АA) is an autoimmune multifactorial disease characterized by increased hair loss as a result of morphological and functional changes in hair follicles. АA is divided into four main forms, among which the most severe is the universal form (UA), in which complete hair loss is possible...
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| Format: | Article |
| Language: | Russian |
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IMA PRESS LLC
2021-10-01
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| Series: | Научно-практическая ревматология |
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| Online Access: | https://rsp.mediar-press.net/rsp/article/view/3086 |
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| author | M. V. Kireeva E. M. Agafonova A. E. Dimitreva K. V. Sakharova S. O. Krasnenko Sh. F. Erdes |
| author_facet | M. V. Kireeva E. M. Agafonova A. E. Dimitreva K. V. Sakharova S. O. Krasnenko Sh. F. Erdes |
| author_sort | M. V. Kireeva |
| collection | DOAJ |
| description | Alopecia areata (АA) is an autoimmune multifactorial disease characterized by increased hair loss as a result of morphological and functional changes in hair follicles. АA is divided into four main forms, among which the most severe is the universal form (UA), in which complete hair loss is possible throughout the body. Alopecia in the practice of a rheumatologist can occur with some systemic diseases of the connective tissue, with the use of high doses of chemotherapy drugs and, more recently, with the use of inhibitors of tumor necrosis factors alpha (TNF-α). The article presents 3 clinical cases of the development of UA during therapy with TNF-α. Possible mechanisms are discussed, as well as the role of pro-inflammatory cytokines in the development of this condition. |
| format | Article |
| id | doaj-art-e0bb44e2ffe4405ca4f00f9107101786 |
| institution | DOAJ |
| issn | 1995-4484 1995-4492 |
| language | Russian |
| publishDate | 2021-10-01 |
| publisher | IMA PRESS LLC |
| record_format | Article |
| series | Научно-практическая ревматология |
| spelling | doaj-art-e0bb44e2ffe4405ca4f00f91071017862025-08-20T03:22:12ZrusIMA PRESS LLCНаучно-практическая ревматология1995-44841995-44922021-10-0159563163710.47360/1995-4484-2021-631-6372754The development of universal alopecia during therapy with TNF-α inhibitors in patients with ankylosing spondylitis: description of three casesM. V. Kireeva0E. M. Agafonova1A. E. Dimitreva2K. V. Sakharova3S. O. Krasnenko4Sh. F. Erdes5V.A. Nasonova Research Institute of RheumatologyV.A. Nasonova Research Institute of RheumatologyV.A. Nasonova Research Institute of RheumatologyV.A. Nasonova Research Institute of RheumatologyV.A. Nasonova Research Institute of RheumatologyV.A. Nasonova Research Institute of RheumatologyAlopecia areata (АA) is an autoimmune multifactorial disease characterized by increased hair loss as a result of morphological and functional changes in hair follicles. АA is divided into four main forms, among which the most severe is the universal form (UA), in which complete hair loss is possible throughout the body. Alopecia in the practice of a rheumatologist can occur with some systemic diseases of the connective tissue, with the use of high doses of chemotherapy drugs and, more recently, with the use of inhibitors of tumor necrosis factors alpha (TNF-α). The article presents 3 clinical cases of the development of UA during therapy with TNF-α. Possible mechanisms are discussed, as well as the role of pro-inflammatory cytokines in the development of this condition.https://rsp.mediar-press.net/rsp/article/view/3086alopecia areatauniversal alopeciaankylosing spondylitistnf-α inhibitors |
| spellingShingle | M. V. Kireeva E. M. Agafonova A. E. Dimitreva K. V. Sakharova S. O. Krasnenko Sh. F. Erdes The development of universal alopecia during therapy with TNF-α inhibitors in patients with ankylosing spondylitis: description of three cases Научно-практическая ревматология alopecia areata universal alopecia ankylosing spondylitis tnf-α inhibitors |
| title | The development of universal alopecia during therapy with TNF-α inhibitors in patients with ankylosing spondylitis: description of three cases |
| title_full | The development of universal alopecia during therapy with TNF-α inhibitors in patients with ankylosing spondylitis: description of three cases |
| title_fullStr | The development of universal alopecia during therapy with TNF-α inhibitors in patients with ankylosing spondylitis: description of three cases |
| title_full_unstemmed | The development of universal alopecia during therapy with TNF-α inhibitors in patients with ankylosing spondylitis: description of three cases |
| title_short | The development of universal alopecia during therapy with TNF-α inhibitors in patients with ankylosing spondylitis: description of three cases |
| title_sort | development of universal alopecia during therapy with tnf α inhibitors in patients with ankylosing spondylitis description of three cases |
| topic | alopecia areata universal alopecia ankylosing spondylitis tnf-α inhibitors |
| url | https://rsp.mediar-press.net/rsp/article/view/3086 |
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