Tissue Engineering of Muscles and Cartilages Using Polyelectrolyte Hydrogels
The prevalent nature of osteoarthritis that causes the erosion of joint surfaces and loss of mobility and muscle dystrophy that weakens the musculoskeletal system and hampers locomotion underlies the importance of developing functional replacement or regeneration of muscle and cartilage tissues. Pol...
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | Advances in Materials Science and Engineering |
| Online Access: | http://dx.doi.org/10.1155/2014/154071 |
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| _version_ | 1849467857767759872 |
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| author | Hyuck Joon Kwon |
| author_facet | Hyuck Joon Kwon |
| author_sort | Hyuck Joon Kwon |
| collection | DOAJ |
| description | The prevalent nature of osteoarthritis that causes the erosion of joint surfaces and loss of mobility and muscle dystrophy that weakens the musculoskeletal system and hampers locomotion underlies the importance of developing functional replacement or regeneration of muscle and cartilage tissues. Polyelectrolyte gels have high potential as cellular scaffolds due to characteristic properties similar to biological matrixes. A number of in vitro and in vivo studies demonstrated that polyelectrolyte gels are useful for replacement and regeneration of muscle and cartilage tissues. In addition, it was also found that polyelectrolyte gels have high biocompatibility, durability, and resistance to biodegradation. Moreover, polyelectrolyte gels can overcome their drawbacks of mechanical behavior by introducing double network into the gel. This paper reviews the current status and recent progress of polyelectrolyte gel-based tissue engineering for repairs of muscle and cartilage tissues. |
| format | Article |
| id | doaj-art-e0ba7f323ce348d9bb8cc5ad1cf4270d |
| institution | Kabale University |
| issn | 1687-8434 1687-8442 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Advances in Materials Science and Engineering |
| spelling | doaj-art-e0ba7f323ce348d9bb8cc5ad1cf4270d2025-08-20T03:26:00ZengWileyAdvances in Materials Science and Engineering1687-84341687-84422014-01-01201410.1155/2014/154071154071Tissue Engineering of Muscles and Cartilages Using Polyelectrolyte HydrogelsHyuck Joon Kwon0Department of Physical Therapy, College of Health Science, Eulji University, Gyeonggi 461-713, Republic of KoreaThe prevalent nature of osteoarthritis that causes the erosion of joint surfaces and loss of mobility and muscle dystrophy that weakens the musculoskeletal system and hampers locomotion underlies the importance of developing functional replacement or regeneration of muscle and cartilage tissues. Polyelectrolyte gels have high potential as cellular scaffolds due to characteristic properties similar to biological matrixes. A number of in vitro and in vivo studies demonstrated that polyelectrolyte gels are useful for replacement and regeneration of muscle and cartilage tissues. In addition, it was also found that polyelectrolyte gels have high biocompatibility, durability, and resistance to biodegradation. Moreover, polyelectrolyte gels can overcome their drawbacks of mechanical behavior by introducing double network into the gel. This paper reviews the current status and recent progress of polyelectrolyte gel-based tissue engineering for repairs of muscle and cartilage tissues.http://dx.doi.org/10.1155/2014/154071 |
| spellingShingle | Hyuck Joon Kwon Tissue Engineering of Muscles and Cartilages Using Polyelectrolyte Hydrogels Advances in Materials Science and Engineering |
| title | Tissue Engineering of Muscles and Cartilages Using Polyelectrolyte Hydrogels |
| title_full | Tissue Engineering of Muscles and Cartilages Using Polyelectrolyte Hydrogels |
| title_fullStr | Tissue Engineering of Muscles and Cartilages Using Polyelectrolyte Hydrogels |
| title_full_unstemmed | Tissue Engineering of Muscles and Cartilages Using Polyelectrolyte Hydrogels |
| title_short | Tissue Engineering of Muscles and Cartilages Using Polyelectrolyte Hydrogels |
| title_sort | tissue engineering of muscles and cartilages using polyelectrolyte hydrogels |
| url | http://dx.doi.org/10.1155/2014/154071 |
| work_keys_str_mv | AT hyuckjoonkwon tissueengineeringofmusclesandcartilagesusingpolyelectrolytehydrogels |