A three-dimensional high throughput assay identifies novel antibacterial molecules with activity against intracellular Shigella

A three-dimensional high throughput assay identifies novel antibacterial molecules with activity against intracellular Shigella

Abstract The Gram-negative bacterial species Shigella is the second leading cause of diarrhea among children in low and middle-income countries (LMICs) and is a World Health Organization (WHO) priority pathogen. Shigella infections are becoming increasing difficult to treat due to antimicrobial resi...

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Main Authors: Voong Vinh Phat, Andrew Shih Teong Lim, Cristina De Cozar-Gallardo, Maria Isabel Castellote Alvaro, Demetrio Muñoz Alvarez, Elena Fernandez Alvaro, Lluis Ballell-Pages, Sonia Lozano-Arias, Stephen Baker
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:npj Antimicrobials and Resistance
Online Access:https://doi.org/10.1038/s44259-025-00110-6
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