Acceptance of booster dose of COVID-19 vaccine and factors influencing it among health care workers at Tikur Anbessa specialized hospital, in Addis Ababa, Ethiopia

Background: The COVID-19 booster dose (BD) was introduced to enhance protection after the initial vaccination series. However, its acceptance remains low, particularly among healthcare workers (HCWs). This study aimed to assess BD acceptance among HCWs at Tikur Anbessa Specialized Hospital, Addis Ab...

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Main Authors: Bahja Ahmed Mohammed, Zelalem Tilahun Tesfaye, Fikreselam Habte Hailemariam, Chalelgn Kassaw Belete
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Clinical Epidemiology and Global Health
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Online Access:http://www.sciencedirect.com/science/article/pii/S2213398425001162
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author Bahja Ahmed Mohammed
Zelalem Tilahun Tesfaye
Fikreselam Habte Hailemariam
Chalelgn Kassaw Belete
author_facet Bahja Ahmed Mohammed
Zelalem Tilahun Tesfaye
Fikreselam Habte Hailemariam
Chalelgn Kassaw Belete
author_sort Bahja Ahmed Mohammed
collection DOAJ
description Background: The COVID-19 booster dose (BD) was introduced to enhance protection after the initial vaccination series. However, its acceptance remains low, particularly among healthcare workers (HCWs). This study aimed to assess BD acceptance among HCWs at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia, and identify the factors influencing their decision. Methodology: A cross-sectional study was conducted among 423 HCWs from May to June 2022. Data were collected using a self-administered questionnaire and a convenient sampling technique. Descriptive and inferential analyses were performed using SPSS version 25. Binary logistic regression was applied to identify factors associated with BD acceptance. Results: A total of 399 HCWs completed the survey, with 51.4 % male, 80.5 % health professionals, and 60.2 % aged 18–30 years. More than half had no prior COVID-19 infection. Despite 86.5 % holding favorable attitudes toward BD, only 28.6 % accepted it. BD acceptance was significantly higher among HCWs aged 31–40 years (AOR = 2.21), 41–50 years (AOR = 4.14), and over 50 years (AOR = 6.00) compared to those aged 18–30 years. Married individuals (AOR = 1.82), those with post-vaccination COVID-19 infection (AOR = 1.94), and those with a favorable attitude toward BD (AOR = 16.74) were more likely to accept it. Conclusion: Less than one-third of HCWs accepted the COVID-19 BD. Older age, marital status, prior post-vaccination COVID-19 infection, and positive attitudes toward vaccination were significant predictors. Low acceptance among HCWs may influence public confidence in immunization, necessitating targeted interventions to improve uptake.
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spelling doaj-art-e0b00482c0244c8faa1613ee153678272025-08-20T03:14:22ZengElsevierClinical Epidemiology and Global Health2213-39842025-05-013310202710.1016/j.cegh.2025.102027Acceptance of booster dose of COVID-19 vaccine and factors influencing it among health care workers at Tikur Anbessa specialized hospital, in Addis Ababa, EthiopiaBahja Ahmed Mohammed0Zelalem Tilahun Tesfaye1Fikreselam Habte Hailemariam2Chalelgn Kassaw Belete3Department of Pharmacology and Clinical Pharmacy, School of Pharmacy, College of Health Sciences, Addis Ababa University, the Federal Democratic Republic of EthiopiaDepartment of Pharmacology and Clinical Pharmacy, School of Pharmacy, College of Health Sciences, Addis Ababa University, the Federal Democratic Republic of EthiopiaDepartment of Pharmacology and Clinical Pharmacy, School of Pharmacy, College of Health Sciences, Addis Ababa University, the Federal Democratic Republic of EthiopiaCorresponding author.; Department of Pharmacology and Clinical Pharmacy, School of Pharmacy, College of Health Sciences, Addis Ababa University, the Federal Democratic Republic of EthiopiaBackground: The COVID-19 booster dose (BD) was introduced to enhance protection after the initial vaccination series. However, its acceptance remains low, particularly among healthcare workers (HCWs). This study aimed to assess BD acceptance among HCWs at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia, and identify the factors influencing their decision. Methodology: A cross-sectional study was conducted among 423 HCWs from May to June 2022. Data were collected using a self-administered questionnaire and a convenient sampling technique. Descriptive and inferential analyses were performed using SPSS version 25. Binary logistic regression was applied to identify factors associated with BD acceptance. Results: A total of 399 HCWs completed the survey, with 51.4 % male, 80.5 % health professionals, and 60.2 % aged 18–30 years. More than half had no prior COVID-19 infection. Despite 86.5 % holding favorable attitudes toward BD, only 28.6 % accepted it. BD acceptance was significantly higher among HCWs aged 31–40 years (AOR = 2.21), 41–50 years (AOR = 4.14), and over 50 years (AOR = 6.00) compared to those aged 18–30 years. Married individuals (AOR = 1.82), those with post-vaccination COVID-19 infection (AOR = 1.94), and those with a favorable attitude toward BD (AOR = 16.74) were more likely to accept it. Conclusion: Less than one-third of HCWs accepted the COVID-19 BD. Older age, marital status, prior post-vaccination COVID-19 infection, and positive attitudes toward vaccination were significant predictors. Low acceptance among HCWs may influence public confidence in immunization, necessitating targeted interventions to improve uptake.http://www.sciencedirect.com/science/article/pii/S2213398425001162AcceptanceBooster dose vaccineCOVID-19Healthcare workersTikur Anbessa specialized hospitalEthiopia
spellingShingle Bahja Ahmed Mohammed
Zelalem Tilahun Tesfaye
Fikreselam Habte Hailemariam
Chalelgn Kassaw Belete
Acceptance of booster dose of COVID-19 vaccine and factors influencing it among health care workers at Tikur Anbessa specialized hospital, in Addis Ababa, Ethiopia
Clinical Epidemiology and Global Health
Acceptance
Booster dose vaccine
COVID-19
Healthcare workers
Tikur Anbessa specialized hospital
Ethiopia
title Acceptance of booster dose of COVID-19 vaccine and factors influencing it among health care workers at Tikur Anbessa specialized hospital, in Addis Ababa, Ethiopia
title_full Acceptance of booster dose of COVID-19 vaccine and factors influencing it among health care workers at Tikur Anbessa specialized hospital, in Addis Ababa, Ethiopia
title_fullStr Acceptance of booster dose of COVID-19 vaccine and factors influencing it among health care workers at Tikur Anbessa specialized hospital, in Addis Ababa, Ethiopia
title_full_unstemmed Acceptance of booster dose of COVID-19 vaccine and factors influencing it among health care workers at Tikur Anbessa specialized hospital, in Addis Ababa, Ethiopia
title_short Acceptance of booster dose of COVID-19 vaccine and factors influencing it among health care workers at Tikur Anbessa specialized hospital, in Addis Ababa, Ethiopia
title_sort acceptance of booster dose of covid 19 vaccine and factors influencing it among health care workers at tikur anbessa specialized hospital in addis ababa ethiopia
topic Acceptance
Booster dose vaccine
COVID-19
Healthcare workers
Tikur Anbessa specialized hospital
Ethiopia
url http://www.sciencedirect.com/science/article/pii/S2213398425001162
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