Adherence and influencing factors of high-flow nasal cannula humidified oxygen therapy in elderly patients with stable chronic obstructive pulmonary disease: A meta-analysis
OBJECTIVE: The objective of the study was to systematically evaluate and perform a meta-analysis on the adherence to high-flow nasal cannula (HFNC) humidified oxygen therapy and its influencing factors in elderly patients with stable chronic obstructive pulmonary disease (COPD). METHODS: Relevant li...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2025-01-01
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| Series: | Annals of Thoracic Medicine |
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| Online Access: | https://journals.lww.com/10.4103/atm.atm_151_24 |
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| _version_ | 1832087849790341120 |
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| author | Yang Yang Ting-Ting Liu Dong-Mei Li Xue-Ling Ren Zheng Luo Xue-Li Chen Ying-Zhen Du Yan-Shuang Cheng |
| author_facet | Yang Yang Ting-Ting Liu Dong-Mei Li Xue-Ling Ren Zheng Luo Xue-Li Chen Ying-Zhen Du Yan-Shuang Cheng |
| author_sort | Yang Yang |
| collection | DOAJ |
| description | OBJECTIVE:
The objective of the study was to systematically evaluate and perform a meta-analysis on the adherence to high-flow nasal cannula (HFNC) humidified oxygen therapy and its influencing factors in elderly patients with stable chronic obstructive pulmonary disease (COPD).
METHODS:
Relevant literature on HFNC and COPD was retrieved from PubMed, EMbase, Web of Science, and Cochrane Library databases. Cross-sectional studies, case–control studies, and cohort studies were included. Screening and quality assessment were conducted using Endnote X9 software. Quality scores were assigned using the Newcastle–Ottawa Scale and the AHRQ assessment tool. Basic information, sample size, and adherence-related factors were extracted, and heterogeneity and publication bias were assessed.
RESULTS:
A total of 321 articles were initially identified, with 8 English articles involving 325 patients included after screening. Quality assessment yielded five high-quality articles (score > 8), two medium-quality articles (score = 7), and one low-quality article (score = 6). Meta-analysis results showed a COPD patient HFNC adherence rate of 32.7%. Negative factors included the number of acute exacerbations (odds ratio [OR] =2.17), adverse reactions (OR = 4.13), regular follow-up (OR = 9.45), educational level (OR = 5.38), and concurrent medications (OR = 4.71). Positive factors included age < 70 years (OR = 0.45), duration of use (OR = 0.30), inhalation technique (OR = 0.31), treatment satisfaction (OR = 0.35), and adverse reactions (OR = 0.15). Funnel plot and Egger’s test results indicated minimal publication bias.
CONCLUSION:
Adherence to HFNC in elderly COPD patients is relatively low, influenced by negative factors such as the number of acute exacerbations, adverse reactions, regular follow-up, educational level, and concurrent medications. Positive factors include age < 70 years, duration of use, inhalation technique, treatment satisfaction, and adverse reactions. |
| format | Article |
| id | doaj-art-e0adb2ba9d30439ca54a8e6cbd74f179 |
| institution | Kabale University |
| issn | 1817-1737 1998-3557 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Annals of Thoracic Medicine |
| spelling | doaj-art-e0adb2ba9d30439ca54a8e6cbd74f1792025-02-06T04:51:14ZengWolters Kluwer Medknow PublicationsAnnals of Thoracic Medicine1817-17371998-35572025-01-01201495510.4103/atm.atm_151_24Adherence and influencing factors of high-flow nasal cannula humidified oxygen therapy in elderly patients with stable chronic obstructive pulmonary disease: A meta-analysisYang YangTing-Ting LiuDong-Mei LiXue-Ling RenZheng LuoXue-Li ChenYing-Zhen DuYan-Shuang ChengOBJECTIVE: The objective of the study was to systematically evaluate and perform a meta-analysis on the adherence to high-flow nasal cannula (HFNC) humidified oxygen therapy and its influencing factors in elderly patients with stable chronic obstructive pulmonary disease (COPD). METHODS: Relevant literature on HFNC and COPD was retrieved from PubMed, EMbase, Web of Science, and Cochrane Library databases. Cross-sectional studies, case–control studies, and cohort studies were included. Screening and quality assessment were conducted using Endnote X9 software. Quality scores were assigned using the Newcastle–Ottawa Scale and the AHRQ assessment tool. Basic information, sample size, and adherence-related factors were extracted, and heterogeneity and publication bias were assessed. RESULTS: A total of 321 articles were initially identified, with 8 English articles involving 325 patients included after screening. Quality assessment yielded five high-quality articles (score > 8), two medium-quality articles (score = 7), and one low-quality article (score = 6). Meta-analysis results showed a COPD patient HFNC adherence rate of 32.7%. Negative factors included the number of acute exacerbations (odds ratio [OR] =2.17), adverse reactions (OR = 4.13), regular follow-up (OR = 9.45), educational level (OR = 5.38), and concurrent medications (OR = 4.71). Positive factors included age < 70 years (OR = 0.45), duration of use (OR = 0.30), inhalation technique (OR = 0.31), treatment satisfaction (OR = 0.35), and adverse reactions (OR = 0.15). Funnel plot and Egger’s test results indicated minimal publication bias. CONCLUSION: Adherence to HFNC in elderly COPD patients is relatively low, influenced by negative factors such as the number of acute exacerbations, adverse reactions, regular follow-up, educational level, and concurrent medications. Positive factors include age < 70 years, duration of use, inhalation technique, treatment satisfaction, and adverse reactions.https://journals.lww.com/10.4103/atm.atm_151_24adherencechronic obstructive pulmonary diseaseelderly patientshigh-flow nasal cannula humidified oxygen therapymeta-analysis |
| spellingShingle | Yang Yang Ting-Ting Liu Dong-Mei Li Xue-Ling Ren Zheng Luo Xue-Li Chen Ying-Zhen Du Yan-Shuang Cheng Adherence and influencing factors of high-flow nasal cannula humidified oxygen therapy in elderly patients with stable chronic obstructive pulmonary disease: A meta-analysis Annals of Thoracic Medicine adherence chronic obstructive pulmonary disease elderly patients high-flow nasal cannula humidified oxygen therapy meta-analysis |
| title | Adherence and influencing factors of high-flow nasal cannula humidified oxygen therapy in elderly patients with stable chronic obstructive pulmonary disease: A meta-analysis |
| title_full | Adherence and influencing factors of high-flow nasal cannula humidified oxygen therapy in elderly patients with stable chronic obstructive pulmonary disease: A meta-analysis |
| title_fullStr | Adherence and influencing factors of high-flow nasal cannula humidified oxygen therapy in elderly patients with stable chronic obstructive pulmonary disease: A meta-analysis |
| title_full_unstemmed | Adherence and influencing factors of high-flow nasal cannula humidified oxygen therapy in elderly patients with stable chronic obstructive pulmonary disease: A meta-analysis |
| title_short | Adherence and influencing factors of high-flow nasal cannula humidified oxygen therapy in elderly patients with stable chronic obstructive pulmonary disease: A meta-analysis |
| title_sort | adherence and influencing factors of high flow nasal cannula humidified oxygen therapy in elderly patients with stable chronic obstructive pulmonary disease a meta analysis |
| topic | adherence chronic obstructive pulmonary disease elderly patients high-flow nasal cannula humidified oxygen therapy meta-analysis |
| url | https://journals.lww.com/10.4103/atm.atm_151_24 |
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