Allosteric activation mechanism of DriD, a WYL-domain containing transcription regulator

Abstract WYL-domain containing transcription factors regulate fundamental processes in bacterial physiology, yet how these proteins sense cellular cues to elicit an allosteric response is not well understood. Here we describe the allosteric activation mechanism of DriD, a Caulobacter crescentus homo...

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Bibliographic Details
Main Authors: Emily Cannistraci, Bindu Y. Srinivasu, Jose Chavez Orozco, Kevin Gozzi, Thomas E. Wales, Maria A. Schumacher
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-025-08111-x
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