Programmed Transformation of Osteogenesis Microenvironment by a Multifunctional Hydrogel to Enhance Repair of Infectious Bone Defects

Programmed Transformation of Osteogenesis Microenvironment by a Multifunctional Hydrogel to Enhance Repair of Infectious Bone Defects

Abstract Repair of infectious bone defects remains a serious problem in clinical practice owing to the high risk of infection and excessive reactive oxygen species (ROS) during the early stage, and the residual bacteria and delayed Osseo integrated interface in the later stage, which jointly creates...

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Main Authors: En Xie, Zhangqin Yuan, Qianglong Chen, Jie Hu, Jiaying Li, Kexin Li, Huan Wang, Jinjin Ma, Bin Meng, Ruoxi Zhang, Haijiao Mao, Ting Liang, Lijie Wang, Chaoyong Liu, Bin Li, Fengxuan Han
Format: Article
Language:English
Published: Wiley 2025-03-01
Series:Advanced Science
Subjects:
antimicrobial property
hydrogel
infected bone defects
melatonin carbon dot
microenvironment
osteogenesis
Online Access:https://doi.org/10.1002/advs.202409683
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