Procalcitonin as New Proinflammatory Marker in Burn Patients
Procalcitonin (PCT) is a 116 amino acid peptide with a sequence identical to that of prohormone of calcitonin but devoid of hormonal activity. The aim of this study was to determine PCT and it using as a new prognostic pro-inflammatory marker in burn patients and determine the role of PCT level as a...
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Erbil Polytechnic University
2021-06-01
|
| Series: | Polytechnic Journal |
| Subjects: | |
| Online Access: | https://polytechnic-journal.epu.edu.iq/home/vol11/iss1/12 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850166323257016320 |
|---|---|
| author | Amer A. Khaleel Ruqaya M. Al-Barzinji |
| author_facet | Amer A. Khaleel Ruqaya M. Al-Barzinji |
| author_sort | Amer A. Khaleel |
| collection | DOAJ |
| description | Procalcitonin (PCT) is a 116 amino acid peptide with a sequence identical to that of prohormone of calcitonin
but devoid of hormonal activity. The aim of this study was to determine PCT and it using as a new prognostic
pro-inflammatory marker in burn patients and determine the role of PCT level as a mortality indicator in survival
and non-survival burn patients. The burn patients in this study were divided into four groups according to
the percentage of total body surface area burned carry out on (50) burn patients admitted to the burn unit
in West Erbil Emergency Hospital in Erbil governorate and (20) apparently the healthy non-burn individuals
who regarded as healthy control group (HC) in this study from February 2012 to April 2012. Out of 50
burnt patients, 20 patients were second sampled to follow-up their immune profile. Regarding PCT there
were significant differences (P < 0.05) observed between the mean serum concentration of PCT belong to
18 burn patients of 1st group (G1) (1.24 ± 0.82), 23 patients of 2nd group (G2) (1.52 ± 0.76), six patients
of 3rd group (G3) (2. 16 ± 0.11), and three burn patients of 4th group (G4) (6.5 ± 2.87) with mean serum
concentration of 18 HC (0.02 ± 0.006). Significant differences obtained when compared to G3 (2.16 ± 0.11)
versus G4 (6.5 ± 2.87) using the F-test and t-test. Results show that PCT is a highly productive laboratory
parameter involving an easy and rapid beside test for diagnosis and prognosis mortality in burn patients. |
| format | Article |
| id | doaj-art-e0a3be35168f4573bc2091f7c95d2ee2 |
| institution | OA Journals |
| issn | 2707-7799 |
| language | English |
| publishDate | 2021-06-01 |
| publisher | Erbil Polytechnic University |
| record_format | Article |
| series | Polytechnic Journal |
| spelling | doaj-art-e0a3be35168f4573bc2091f7c95d2ee22025-08-20T02:21:29ZengErbil Polytechnic UniversityPolytechnic Journal2707-77992021-06-011115862https://doi.org/10.25156/ptj.v11n1y2021.pp58-62Procalcitonin as New Proinflammatory Marker in Burn PatientsAmer A. Khaleel0Ruqaya M. Al-Barzinji1Department of Medical Microbiology, College of Health Sciences, Hawler Medical University, Erbil, Kurdistan Region, IraqDepartment Basic Sciences, Microbiology Unit, College of Medicine, Hawler Medical University, Erbil, Kurdistan Region, IraqProcalcitonin (PCT) is a 116 amino acid peptide with a sequence identical to that of prohormone of calcitonin but devoid of hormonal activity. The aim of this study was to determine PCT and it using as a new prognostic pro-inflammatory marker in burn patients and determine the role of PCT level as a mortality indicator in survival and non-survival burn patients. The burn patients in this study were divided into four groups according to the percentage of total body surface area burned carry out on (50) burn patients admitted to the burn unit in West Erbil Emergency Hospital in Erbil governorate and (20) apparently the healthy non-burn individuals who regarded as healthy control group (HC) in this study from February 2012 to April 2012. Out of 50 burnt patients, 20 patients were second sampled to follow-up their immune profile. Regarding PCT there were significant differences (P < 0.05) observed between the mean serum concentration of PCT belong to 18 burn patients of 1st group (G1) (1.24 ± 0.82), 23 patients of 2nd group (G2) (1.52 ± 0.76), six patients of 3rd group (G3) (2. 16 ± 0.11), and three burn patients of 4th group (G4) (6.5 ± 2.87) with mean serum concentration of 18 HC (0.02 ± 0.006). Significant differences obtained when compared to G3 (2.16 ± 0.11) versus G4 (6.5 ± 2.87) using the F-test and t-test. Results show that PCT is a highly productive laboratory parameter involving an easy and rapid beside test for diagnosis and prognosis mortality in burn patients.https://polytechnic-journal.epu.edu.iq/home/vol11/iss1/12procalcitonin;total body surface area;burn patient |
| spellingShingle | Amer A. Khaleel Ruqaya M. Al-Barzinji Procalcitonin as New Proinflammatory Marker in Burn Patients Polytechnic Journal procalcitonin; total body surface area; burn patient |
| title | Procalcitonin as New Proinflammatory Marker in Burn Patients |
| title_full | Procalcitonin as New Proinflammatory Marker in Burn Patients |
| title_fullStr | Procalcitonin as New Proinflammatory Marker in Burn Patients |
| title_full_unstemmed | Procalcitonin as New Proinflammatory Marker in Burn Patients |
| title_short | Procalcitonin as New Proinflammatory Marker in Burn Patients |
| title_sort | procalcitonin as new proinflammatory marker in burn patients |
| topic | procalcitonin; total body surface area; burn patient |
| url | https://polytechnic-journal.epu.edu.iq/home/vol11/iss1/12 |
| work_keys_str_mv | AT amerakhaleel procalcitoninasnewproinflammatorymarkerinburnpatients AT ruqayamalbarzinji procalcitoninasnewproinflammatorymarkerinburnpatients |