Autoimmune Gastritis: Focus on Endoscopic and Morphological Characteristics

Aim: tosystematize the literature data on endoscopic semiotics and morphological changes in the gastric mucosa in autoimmune gastritis.Key points. Autoimmune gastritis is associated with an increased risk of developing adenocarcinoma and neuroendocrine tumours of the stomach. Clarification of diagno...

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Main Authors: A. P. Kiryukhin, A. S. Tertychnyy, P. V. Pavlov, A. A. Fedorenko, D. P. Nagornaya, N. S. Marenich, E. A. Losik, E. Yu. Yuryeva, T. L. Lapina
Format: Article
Language:Russian
Published: Gastro LLC 2024-03-01
Series:Российский журнал гастроэнтерологии, гепатологии, колопроктологии
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Online Access:https://www.gastro-j.ru/jour/article/view/831
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author A. P. Kiryukhin
A. S. Tertychnyy
P. V. Pavlov
A. A. Fedorenko
D. P. Nagornaya
N. S. Marenich
E. A. Losik
E. Yu. Yuryeva
T. L. Lapina
author_facet A. P. Kiryukhin
A. S. Tertychnyy
P. V. Pavlov
A. A. Fedorenko
D. P. Nagornaya
N. S. Marenich
E. A. Losik
E. Yu. Yuryeva
T. L. Lapina
author_sort A. P. Kiryukhin
collection DOAJ
description Aim: tosystematize the literature data on endoscopic semiotics and morphological changes in the gastric mucosa in autoimmune gastritis.Key points. Autoimmune gastritis is associated with an increased risk of developing adenocarcinoma and neuroendocrine tumours of the stomach. Clarification of diagnostic criteria for autoimmune gastritis is essential for gastroenterological practice. The diagnosis is based on the results of endoscopic and histological examination, and on data from laboratory tests. Isolated atrophy of the mucous membrane of the body of the stomach, the presence of difficult-to-wash creamy mucus, changes in the mucous membrane like “shed skin”, and the presence of whitish globule-like foci are typical endoscopic signs of autoimmune gastritis. Widespread pseudopyloric metaplasia, focal intestinal and pseudopancreatic metaplasia, hyperplasia of the ridges of the mucous membrane of the body of the stomach and their relationship to the glandular layer as in the antrum allow during a morphological study considering clinical data to suspect and verify autoimmune gastritis.Conclusion. During instrumental examination, knowledge of endoscopic symptoms and pathognomonic morphological changes is important for the timely diagnosis of autoimmune gastritis.
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publishDate 2024-03-01
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series Российский журнал гастроэнтерологии, гепатологии, колопроктологии
spelling doaj-art-e0a2ba70b04244fba72a05cb7bec55ae2025-02-10T16:14:38ZrusGastro LLCРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии1382-43762658-66732024-03-01341586910.22416/1382-4376-2024-34-1-58-69591Autoimmune Gastritis: Focus on Endoscopic and Morphological CharacteristicsA. P. Kiryukhin0A. S. Tertychnyy1P. V. Pavlov2A. A. Fedorenko3D. P. Nagornaya4N. S. Marenich5E. A. Losik6E. Yu. Yuryeva7T. L. Lapina8I.M. Sechenov First Moscow State Medical University (Sechenov University)I.M. Sechenov First Moscow State Medical University (Sechenov University)I.M. Sechenov First Moscow State Medical University (Sechenov University)I.M. Sechenov First Moscow State Medical University (Sechenov University)I.M. Sechenov First Moscow State Medical University (Sechenov University)Morozov Children's City Clinical Hospital of the Moscow Health DepartmentI.M. Sechenov First Moscow State Medical University (Sechenov University)I.M. Sechenov First Moscow State Medical University (Sechenov University)I.M. Sechenov First Moscow State Medical University (Sechenov University)Aim: tosystematize the literature data on endoscopic semiotics and morphological changes in the gastric mucosa in autoimmune gastritis.Key points. Autoimmune gastritis is associated with an increased risk of developing adenocarcinoma and neuroendocrine tumours of the stomach. Clarification of diagnostic criteria for autoimmune gastritis is essential for gastroenterological practice. The diagnosis is based on the results of endoscopic and histological examination, and on data from laboratory tests. Isolated atrophy of the mucous membrane of the body of the stomach, the presence of difficult-to-wash creamy mucus, changes in the mucous membrane like “shed skin”, and the presence of whitish globule-like foci are typical endoscopic signs of autoimmune gastritis. Widespread pseudopyloric metaplasia, focal intestinal and pseudopancreatic metaplasia, hyperplasia of the ridges of the mucous membrane of the body of the stomach and their relationship to the glandular layer as in the antrum allow during a morphological study considering clinical data to suspect and verify autoimmune gastritis.Conclusion. During instrumental examination, knowledge of endoscopic symptoms and pathognomonic morphological changes is important for the timely diagnosis of autoimmune gastritis.https://www.gastro-j.ru/jour/article/view/831autoimmune gastritisendoscopybiopsyatrophyhelicobacter pylori
spellingShingle A. P. Kiryukhin
A. S. Tertychnyy
P. V. Pavlov
A. A. Fedorenko
D. P. Nagornaya
N. S. Marenich
E. A. Losik
E. Yu. Yuryeva
T. L. Lapina
Autoimmune Gastritis: Focus on Endoscopic and Morphological Characteristics
Российский журнал гастроэнтерологии, гепатологии, колопроктологии
autoimmune gastritis
endoscopy
biopsy
atrophy
helicobacter pylori
title Autoimmune Gastritis: Focus on Endoscopic and Morphological Characteristics
title_full Autoimmune Gastritis: Focus on Endoscopic and Morphological Characteristics
title_fullStr Autoimmune Gastritis: Focus on Endoscopic and Morphological Characteristics
title_full_unstemmed Autoimmune Gastritis: Focus on Endoscopic and Morphological Characteristics
title_short Autoimmune Gastritis: Focus on Endoscopic and Morphological Characteristics
title_sort autoimmune gastritis focus on endoscopic and morphological characteristics
topic autoimmune gastritis
endoscopy
biopsy
atrophy
helicobacter pylori
url https://www.gastro-j.ru/jour/article/view/831
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AT astertychnyy autoimmunegastritisfocusonendoscopicandmorphologicalcharacteristics
AT pvpavlov autoimmunegastritisfocusonendoscopicandmorphologicalcharacteristics
AT aafedorenko autoimmunegastritisfocusonendoscopicandmorphologicalcharacteristics
AT dpnagornaya autoimmunegastritisfocusonendoscopicandmorphologicalcharacteristics
AT nsmarenich autoimmunegastritisfocusonendoscopicandmorphologicalcharacteristics
AT ealosik autoimmunegastritisfocusonendoscopicandmorphologicalcharacteristics
AT eyuyuryeva autoimmunegastritisfocusonendoscopicandmorphologicalcharacteristics
AT tllapina autoimmunegastritisfocusonendoscopicandmorphologicalcharacteristics