Mesenchymal stem cells from perinatal tissues promote diabetic wound healing via PI3K/AKT activation

Mesenchymal stem cells from perinatal tissues promote diabetic wound healing via PI3K/AKT activation

Abstract Background Diabetic foot ulcers (DFUs) represent a major complication of diabetes, often leading to poor healing outcomes with conventional treatments. Mesenchymal stem cell (MSC) therapies have emerged as a promising alternative, given their potential to modulate various pathways involved...

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Bibliographic Details
Main Authors: Jiawei Huang, Qingwen Deng, Lai Ling Tsang, Guozhu Chang, Jinghui Guo, Ye Chun Ruan, Chi Chiu Wang, Gang Li, Hon Fai Chan, Xiaohu Zhang, Xiaohua Jiang
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Stem Cell Research & Therapy
Subjects:
Diabetic wound healing
Placenta
MSCs
Hydrogel
PI3K/AKT
Online Access:https://doi.org/10.1186/s13287-025-04141-8
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