Phosphatidylethanolamine Protects Nucleus Pulposus Cells From Oxidative Stress‐Induced Cellular Senescence and Extracellular Matrix Degradation by Promoting Autophagy

Phosphatidylethanolamine Protects Nucleus Pulposus Cells From Oxidative Stress‐Induced Cellular Senescence and Extracellular Matrix Degradation by Promoting Autophagy

ABSTRACT Background Intervertebral disc degeneration (IDD) is a type of musculoskeletal system diseases that prevail widely in human society, exerting a substantial economic burden on society. The extensive aggregation of senescent nucleus pulposus (NP) cells within the discs is a significant charac...

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Bibliographic Details
Main Authors: Yijun Dong, Chuanfu Li, Shuangshuang Tu, Mingkai Liu, Kai Lv, Liqun Duan, Feng Zhang, Haiping Cai, Xi Chen, Wenzhi Zhang
Format: Article
Language:English
Published: Wiley 2025-06-01
Series:JOR Spine
Subjects:
autophagy
cellular senescence
intervertebral disc degeneration
metabolomics analysis
phosphatidylethanolamine
Online Access:https://doi.org/10.1002/jsp2.70058
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