WDR62 Regulates Early Neural and Glial Progenitor Specification of Human Pluripotent Stem Cells

WDR62 Regulates Early Neural and Glial Progenitor Specification of Human Pluripotent Stem Cells

Mutations in WD40-repeat protein 62 (WDR62) are commonly associated with primary microcephaly and other developmental cortical malformations. We used human pluripotent stem cells (hPSC) to examine WDR62 function during human neural differentiation and model early stages of human corticogenesis. Neur...

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Bibliographic Details
Main Authors: Abdullah J. Alshawaf, Ana Antonic, Efstratios Skafidas, Dominic Chi-Hung Ng, Mirella Dottori
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Stem Cells International
Online Access:http://dx.doi.org/10.1155/2017/7848932
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