Antibacterial Therapeutic Agents Composed of Functional Biological Molecules

Antibacterial agents are a group of materials that selectively destroy bacteria by interfering with bacterial growth or survival. With the emergence of resistance phenomenon of bacterial pathogens to current antibiotics, new drugs are frequently entering into the market along with the existing drugs...

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Main Authors: Dawei Li, Bing Zhou, Bei Lv
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2020/6578579
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author Dawei Li
Bing Zhou
Bei Lv
author_facet Dawei Li
Bing Zhou
Bei Lv
author_sort Dawei Li
collection DOAJ
description Antibacterial agents are a group of materials that selectively destroy bacteria by interfering with bacterial growth or survival. With the emergence of resistance phenomenon of bacterial pathogens to current antibiotics, new drugs are frequently entering into the market along with the existing drugs, and the alternative compounds with antibacterial functions are being explored. Due to the advantages of their inherent biochemical and biophysical properties including precise targeting ability, biocompatibility, biodegradability, long blood circulation time, and low cytotoxicity, biomolecules such as peptides, carbohydrates, and nucleic acids have huge potential for the antimicrobial application and have been extensively studied in recent years. In this review, antimicrobial therapeutic agents composed of three kinds of functional biological molecules were summarized. In addition, the research progress of antibacterial mechanism, chemical modification, and nanoparticle coupling of those biomolecules were also discussed.
format Article
id doaj-art-e08dae5c007444369d6afa96baa9ab86
institution OA Journals
issn 2090-9063
2090-9071
language English
publishDate 2020-01-01
publisher Wiley
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series Journal of Chemistry
spelling doaj-art-e08dae5c007444369d6afa96baa9ab862025-08-20T02:21:30ZengWileyJournal of Chemistry2090-90632090-90712020-01-01202010.1155/2020/65785796578579Antibacterial Therapeutic Agents Composed of Functional Biological MoleculesDawei Li0Bing Zhou1Bei Lv2College of Biology and the Environment, The Southern Modern Forestry Collaborative Innovation Center, Nanjing Forestry University, 159 Longpan Road, Nanjing 210037, ChinaCollege of Biology and the Environment, The Southern Modern Forestry Collaborative Innovation Center, Nanjing Forestry University, 159 Longpan Road, Nanjing 210037, ChinaJiangsu Key Laboratory for Biofunctional Molecules, College of Life Science and Chemistry, Jiangsu Second Normal University, Nanjing 210013, ChinaAntibacterial agents are a group of materials that selectively destroy bacteria by interfering with bacterial growth or survival. With the emergence of resistance phenomenon of bacterial pathogens to current antibiotics, new drugs are frequently entering into the market along with the existing drugs, and the alternative compounds with antibacterial functions are being explored. Due to the advantages of their inherent biochemical and biophysical properties including precise targeting ability, biocompatibility, biodegradability, long blood circulation time, and low cytotoxicity, biomolecules such as peptides, carbohydrates, and nucleic acids have huge potential for the antimicrobial application and have been extensively studied in recent years. In this review, antimicrobial therapeutic agents composed of three kinds of functional biological molecules were summarized. In addition, the research progress of antibacterial mechanism, chemical modification, and nanoparticle coupling of those biomolecules were also discussed.http://dx.doi.org/10.1155/2020/6578579
spellingShingle Dawei Li
Bing Zhou
Bei Lv
Antibacterial Therapeutic Agents Composed of Functional Biological Molecules
Journal of Chemistry
title Antibacterial Therapeutic Agents Composed of Functional Biological Molecules
title_full Antibacterial Therapeutic Agents Composed of Functional Biological Molecules
title_fullStr Antibacterial Therapeutic Agents Composed of Functional Biological Molecules
title_full_unstemmed Antibacterial Therapeutic Agents Composed of Functional Biological Molecules
title_short Antibacterial Therapeutic Agents Composed of Functional Biological Molecules
title_sort antibacterial therapeutic agents composed of functional biological molecules
url http://dx.doi.org/10.1155/2020/6578579
work_keys_str_mv AT daweili antibacterialtherapeuticagentscomposedoffunctionalbiologicalmolecules
AT bingzhou antibacterialtherapeuticagentscomposedoffunctionalbiologicalmolecules
AT beilv antibacterialtherapeuticagentscomposedoffunctionalbiologicalmolecules