In-depth hemodynamic assessment in acute mild stroke patients with large vessel occlusion or stenosis
Abstract Objective Acute treatment in mild stroke patients with acute anterior circulation large vessel occlusion/stenosis (AACLVO/S) had limited evidence. Hemodynamic play an important role in neurological deterioration. We aimed to investigate predictor value of hemodynamic assessment for clinical...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2024-11-01
|
| Series: | BMC Neurology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12883-024-03939-y |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850194728679636992 |
|---|---|
| author | Ge Tian Jing Huang Jiajia Zhu Qiheng Wu Jia Yin |
| author_facet | Ge Tian Jing Huang Jiajia Zhu Qiheng Wu Jia Yin |
| author_sort | Ge Tian |
| collection | DOAJ |
| description | Abstract Objective Acute treatment in mild stroke patients with acute anterior circulation large vessel occlusion/stenosis (AACLVO/S) had limited evidence. Hemodynamic play an important role in neurological deterioration. We aimed to investigate predictor value of hemodynamic assessment for clinical outcome predicting and guiding individual therapeutic decisions in those patients. Methods We retrospectively analyze the stroke database in our stroke center. We recruited patients with mild stroke, defined by National Institutes of Health Stroke Scale (NIHSS) score ≤ 5, caused by AACLVO/S treated with just medical management (MT). They all received cerebral autoregulation (CA) assessments within 72 h after stroke onset. The primary end point was clinical outcome at 90-day after stroke. Results Logistic regression analysis showed that bilateral higher baseline phase difference (PD) were independent variables related to favorable 90-day outcome, (OR 0.963, 95% CI 0.936–0.991, p = 0.040; OR 0.943, 95% CI 0.970–0.997; p = 0.008, respectively). The optimal cutoff value of bilateral PD was > 34.97º and > 14.29º respectively. Conclusion CA evaluation can provide hemodynamic status in mild stroke patients with AACLVO/S. |
| format | Article |
| id | doaj-art-e08bbf576d524642a02567b9e8b9dbdc |
| institution | OA Journals |
| issn | 1471-2377 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Neurology |
| spelling | doaj-art-e08bbf576d524642a02567b9e8b9dbdc2025-08-20T02:13:55ZengBMCBMC Neurology1471-23772024-11-012411610.1186/s12883-024-03939-yIn-depth hemodynamic assessment in acute mild stroke patients with large vessel occlusion or stenosisGe Tian0Jing Huang1Jiajia Zhu2Qiheng Wu3Jia Yin4Department of Neurology, Nanfang Hospital, Southern Medical UniversityDepartment of Neurology, Nanfang Hospital, Southern Medical UniversityDepartment of Neurology, Nanfang Hospital, Southern Medical UniversityDepartment of Neurology, Nanfang Hospital, Southern Medical UniversityDepartment of Neurology, Nanfang Hospital, Southern Medical UniversityAbstract Objective Acute treatment in mild stroke patients with acute anterior circulation large vessel occlusion/stenosis (AACLVO/S) had limited evidence. Hemodynamic play an important role in neurological deterioration. We aimed to investigate predictor value of hemodynamic assessment for clinical outcome predicting and guiding individual therapeutic decisions in those patients. Methods We retrospectively analyze the stroke database in our stroke center. We recruited patients with mild stroke, defined by National Institutes of Health Stroke Scale (NIHSS) score ≤ 5, caused by AACLVO/S treated with just medical management (MT). They all received cerebral autoregulation (CA) assessments within 72 h after stroke onset. The primary end point was clinical outcome at 90-day after stroke. Results Logistic regression analysis showed that bilateral higher baseline phase difference (PD) were independent variables related to favorable 90-day outcome, (OR 0.963, 95% CI 0.936–0.991, p = 0.040; OR 0.943, 95% CI 0.970–0.997; p = 0.008, respectively). The optimal cutoff value of bilateral PD was > 34.97º and > 14.29º respectively. Conclusion CA evaluation can provide hemodynamic status in mild stroke patients with AACLVO/S.https://doi.org/10.1186/s12883-024-03939-yCerebral autoregulationMild strokeLarge artery stenosisOutcome |
| spellingShingle | Ge Tian Jing Huang Jiajia Zhu Qiheng Wu Jia Yin In-depth hemodynamic assessment in acute mild stroke patients with large vessel occlusion or stenosis BMC Neurology Cerebral autoregulation Mild stroke Large artery stenosis Outcome |
| title | In-depth hemodynamic assessment in acute mild stroke patients with large vessel occlusion or stenosis |
| title_full | In-depth hemodynamic assessment in acute mild stroke patients with large vessel occlusion or stenosis |
| title_fullStr | In-depth hemodynamic assessment in acute mild stroke patients with large vessel occlusion or stenosis |
| title_full_unstemmed | In-depth hemodynamic assessment in acute mild stroke patients with large vessel occlusion or stenosis |
| title_short | In-depth hemodynamic assessment in acute mild stroke patients with large vessel occlusion or stenosis |
| title_sort | in depth hemodynamic assessment in acute mild stroke patients with large vessel occlusion or stenosis |
| topic | Cerebral autoregulation Mild stroke Large artery stenosis Outcome |
| url | https://doi.org/10.1186/s12883-024-03939-y |
| work_keys_str_mv | AT getian indepthhemodynamicassessmentinacutemildstrokepatientswithlargevesselocclusionorstenosis AT jinghuang indepthhemodynamicassessmentinacutemildstrokepatientswithlargevesselocclusionorstenosis AT jiajiazhu indepthhemodynamicassessmentinacutemildstrokepatientswithlargevesselocclusionorstenosis AT qihengwu indepthhemodynamicassessmentinacutemildstrokepatientswithlargevesselocclusionorstenosis AT jiayin indepthhemodynamicassessmentinacutemildstrokepatientswithlargevesselocclusionorstenosis |