A prospective, randomized clinical trial comparing the effects of three viscoelastics on the corneal endothelium after cataract surgery
Objective: To compare the effects of Amvisc Plus (AP), Duovisc (DV), and Viscoat (VC)on the corneal endothelium of patients who have undergone uncomplicated phacoemulsification cataract surgery. Methods: This is a prospective, randomized trial that involved 60 eyes of 48 patients with age-related...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Philippine Academy of Ophthalmology
2004-03-01
|
| Series: | Philippine Journal of Ophthalmology |
| Online Access: | https://paojournal.com/index.php/pjo/article/view/474 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850207580796747776 |
|---|---|
| author | Harvey S. Uy, MD Kristine E. Bacsal, MD John D.G. Flores, MD Robert Edward Ang, MD Pik Sha Chan, MD |
| author_facet | Harvey S. Uy, MD Kristine E. Bacsal, MD John D.G. Flores, MD Robert Edward Ang, MD Pik Sha Chan, MD |
| author_sort | Harvey S. Uy, MD |
| collection | DOAJ |
| description | Objective: To compare the effects of Amvisc Plus (AP), Duovisc (DV), and Viscoat (VC)on the corneal endothelium of patients who have undergone uncomplicated phacoemulsification cataract surgery.
Methods: This is a prospective, randomized trial that involved 60 eyes of 48 patients with age-related cataracts. The eyes were randomly assigned to receive AP, DV, or VC during phacoemulsification. The main outcome measures were post-operative intraocular pressure (IOP), endothelial cell counts, and corneal thickness.
Results: The mean postoperative IOP were 15.13 ± 2.99 mmHg in the AP group, 15.42 ± 2.35 mmHg in the DV group, and 14.86 ± 5.56 mmHg in the VC group. The average postoperative endothelial cell counts were 2531 ± 420 cells/mm2 in the AP group, 2330 ± 674 cells/mm2 in the DV group, and 2678 ± 471 cells/mm2 in the VC group. The mean postoperative corneal thickness measurements were 566 ± 49 m for the AP group, 561 ± 21 m for the DV group, and 552 ± 27 m for the VC group. No significant differences in all parameters were noted among the three groups.
Conclusion: The results of this study suggest that AP, DV, and VC may be comparable in terms of their ability to protect the corneal endothelium during phacoemulsification. |
| format | Article |
| id | doaj-art-e0879e85adbe45fa8ad1b8868b006bd9 |
| institution | OA Journals |
| issn | 0031-7659 |
| language | English |
| publishDate | 2004-03-01 |
| publisher | Philippine Academy of Ophthalmology |
| record_format | Article |
| series | Philippine Journal of Ophthalmology |
| spelling | doaj-art-e0879e85adbe45fa8ad1b8868b006bd92025-08-20T02:10:28ZengPhilippine Academy of OphthalmologyPhilippine Journal of Ophthalmology0031-76592004-03-012911216474A prospective, randomized clinical trial comparing the effects of three viscoelastics on the corneal endothelium after cataract surgeryHarvey S. Uy, MD0Kristine E. Bacsal, MD1John D.G. Flores, MD2Robert Edward Ang, MD3Pik Sha Chan, MD4Department of Ophthalmology and Visual Sciences University of the Philippines Philippine General Hospital Manila; Asian Eye Institute Makati CityDepartment of Ophthalmology and Visual Sciences University of the Philippines Philippine General Hospital ManilaDepartment of Ophthalmology and Visual Sciences University of the Philippines Philippine General Hospital ManilaAsian Eye Institute Makati CityAsian Eye Institute Makati CityObjective: To compare the effects of Amvisc Plus (AP), Duovisc (DV), and Viscoat (VC)on the corneal endothelium of patients who have undergone uncomplicated phacoemulsification cataract surgery. Methods: This is a prospective, randomized trial that involved 60 eyes of 48 patients with age-related cataracts. The eyes were randomly assigned to receive AP, DV, or VC during phacoemulsification. The main outcome measures were post-operative intraocular pressure (IOP), endothelial cell counts, and corneal thickness. Results: The mean postoperative IOP were 15.13 ± 2.99 mmHg in the AP group, 15.42 ± 2.35 mmHg in the DV group, and 14.86 ± 5.56 mmHg in the VC group. The average postoperative endothelial cell counts were 2531 ± 420 cells/mm2 in the AP group, 2330 ± 674 cells/mm2 in the DV group, and 2678 ± 471 cells/mm2 in the VC group. The mean postoperative corneal thickness measurements were 566 ± 49 m for the AP group, 561 ± 21 m for the DV group, and 552 ± 27 m for the VC group. No significant differences in all parameters were noted among the three groups. Conclusion: The results of this study suggest that AP, DV, and VC may be comparable in terms of their ability to protect the corneal endothelium during phacoemulsification.https://paojournal.com/index.php/pjo/article/view/474 |
| spellingShingle | Harvey S. Uy, MD Kristine E. Bacsal, MD John D.G. Flores, MD Robert Edward Ang, MD Pik Sha Chan, MD A prospective, randomized clinical trial comparing the effects of three viscoelastics on the corneal endothelium after cataract surgery Philippine Journal of Ophthalmology |
| title | A prospective, randomized clinical trial comparing the effects of three viscoelastics on the corneal endothelium after cataract surgery |
| title_full | A prospective, randomized clinical trial comparing the effects of three viscoelastics on the corneal endothelium after cataract surgery |
| title_fullStr | A prospective, randomized clinical trial comparing the effects of three viscoelastics on the corneal endothelium after cataract surgery |
| title_full_unstemmed | A prospective, randomized clinical trial comparing the effects of three viscoelastics on the corneal endothelium after cataract surgery |
| title_short | A prospective, randomized clinical trial comparing the effects of three viscoelastics on the corneal endothelium after cataract surgery |
| title_sort | prospective randomized clinical trial comparing the effects of three viscoelastics on the corneal endothelium after cataract surgery |
| url | https://paojournal.com/index.php/pjo/article/view/474 |
| work_keys_str_mv | AT harveysuymd aprospectiverandomizedclinicaltrialcomparingtheeffectsofthreeviscoelasticsonthecornealendotheliumaftercataractsurgery AT kristineebacsalmd aprospectiverandomizedclinicaltrialcomparingtheeffectsofthreeviscoelasticsonthecornealendotheliumaftercataractsurgery AT johndgfloresmd aprospectiverandomizedclinicaltrialcomparingtheeffectsofthreeviscoelasticsonthecornealendotheliumaftercataractsurgery AT robertedwardangmd aprospectiverandomizedclinicaltrialcomparingtheeffectsofthreeviscoelasticsonthecornealendotheliumaftercataractsurgery AT pikshachanmd aprospectiverandomizedclinicaltrialcomparingtheeffectsofthreeviscoelasticsonthecornealendotheliumaftercataractsurgery AT harveysuymd prospectiverandomizedclinicaltrialcomparingtheeffectsofthreeviscoelasticsonthecornealendotheliumaftercataractsurgery AT kristineebacsalmd prospectiverandomizedclinicaltrialcomparingtheeffectsofthreeviscoelasticsonthecornealendotheliumaftercataractsurgery AT johndgfloresmd prospectiverandomizedclinicaltrialcomparingtheeffectsofthreeviscoelasticsonthecornealendotheliumaftercataractsurgery AT robertedwardangmd prospectiverandomizedclinicaltrialcomparingtheeffectsofthreeviscoelasticsonthecornealendotheliumaftercataractsurgery AT pikshachanmd prospectiverandomizedclinicaltrialcomparingtheeffectsofthreeviscoelasticsonthecornealendotheliumaftercataractsurgery |