Host cellular transcriptional response to respiratory syncytial virus infection in HEp-2 cells: insights from cDNA microarray and quantitative PCR analyses

Host cellular transcriptional response to respiratory syncytial virus infection in HEp-2 cells: insights from cDNA microarray and quantitative PCR analyses

Respiratory syncytial virus (RSV) is a leading cause of lower respiratory tract infections in young children and elderly, worldwide and poses significant risks to immunocompromised individuals. To elucidate host-virus interactions at the transcriptional level, we analyzed differential gene expressio...

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Bibliographic Details
Main Authors: Manoj K. Pastey, Christopher Lupfer
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
respiratory syncytial virus
host-virus interactions
gene expression
host transcriptomic response
microarray
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2025.1613386/full
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