Second Renal Transplantation With Simultaneous Ileal Conduit Creation Following Transplant Nephroureterectomy and Native Cystectomy

ABSTRACT Introduction Postrenal transplant urothelial carcinoma necessitates multidisciplinary treatment. We here report the first case of a patient with transplant ureteral and bladder cancer who underwent transplant nephroureterectomy and cystectomy, followed by a second living donor renal transpl...

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Main Authors: Ayato Ito, Takehiro Ohyama, Kyoko Minamisono, Sho Nishida, Daiki Iwami
Format: Article
Language:English
Published: Wiley 2025-07-01
Series:IJU Case Reports
Subjects:
Online Access:https://doi.org/10.1002/iju5.70044
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author Ayato Ito
Takehiro Ohyama
Kyoko Minamisono
Sho Nishida
Daiki Iwami
author_facet Ayato Ito
Takehiro Ohyama
Kyoko Minamisono
Sho Nishida
Daiki Iwami
author_sort Ayato Ito
collection DOAJ
description ABSTRACT Introduction Postrenal transplant urothelial carcinoma necessitates multidisciplinary treatment. We here report the first case of a patient with transplant ureteral and bladder cancer who underwent transplant nephroureterectomy and cystectomy, followed by a second living donor renal transplantation and ileal conduit creation after a cancer recurrence‐free period. Case Presentation A 78‐year‐old female with end‐stage renal disease who had previously undergone living donor renal transplantation presented with gross hematuria. She was diagnosed with transplant ureteral and bladder cancer and subsequently underwent transplant nephroureterectomy and cystectomy. She was immediately reintroduced to hemodialysis. After a 2‐year cancer‐free period, a second living donor renal transplantation with simultaneous ileal conduit surgery was successfully performed. Currently, the patient remains cancer‐free for 2 years following the second renal transplantation. Conclusion Second renal transplantation and simultaneous ileal conduit creation are alternatives following curative transplant nephrouretero‐cystectomy for post‐transplant urothelial carcinoma.
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publisher Wiley
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series IJU Case Reports
spelling doaj-art-e07fa26b87714d368d165cf140f39a722025-08-20T02:38:09ZengWileyIJU Case Reports2577-171X2025-07-018437738110.1002/iju5.70044Second Renal Transplantation With Simultaneous Ileal Conduit Creation Following Transplant Nephroureterectomy and Native CystectomyAyato Ito0Takehiro Ohyama1Kyoko Minamisono2Sho Nishida3Daiki Iwami4Department of Renal Surgery and Transplantation Jichi Medical University Tochigi JapanDepartment of Renal Surgery and Transplantation Jichi Medical University Tochigi JapanDepartment of Renal Surgery and Transplantation Jichi Medical University Tochigi JapanDepartment of Renal Surgery and Transplantation Jichi Medical University Tochigi JapanDepartment of Renal Surgery and Transplantation Jichi Medical University Tochigi JapanABSTRACT Introduction Postrenal transplant urothelial carcinoma necessitates multidisciplinary treatment. We here report the first case of a patient with transplant ureteral and bladder cancer who underwent transplant nephroureterectomy and cystectomy, followed by a second living donor renal transplantation and ileal conduit creation after a cancer recurrence‐free period. Case Presentation A 78‐year‐old female with end‐stage renal disease who had previously undergone living donor renal transplantation presented with gross hematuria. She was diagnosed with transplant ureteral and bladder cancer and subsequently underwent transplant nephroureterectomy and cystectomy. She was immediately reintroduced to hemodialysis. After a 2‐year cancer‐free period, a second living donor renal transplantation with simultaneous ileal conduit surgery was successfully performed. Currently, the patient remains cancer‐free for 2 years following the second renal transplantation. Conclusion Second renal transplantation and simultaneous ileal conduit creation are alternatives following curative transplant nephrouretero‐cystectomy for post‐transplant urothelial carcinoma.https://doi.org/10.1002/iju5.70044BK virusileal conduitsecond renal transplantationurothelial carcinoma
spellingShingle Ayato Ito
Takehiro Ohyama
Kyoko Minamisono
Sho Nishida
Daiki Iwami
Second Renal Transplantation With Simultaneous Ileal Conduit Creation Following Transplant Nephroureterectomy and Native Cystectomy
IJU Case Reports
BK virus
ileal conduit
second renal transplantation
urothelial carcinoma
title Second Renal Transplantation With Simultaneous Ileal Conduit Creation Following Transplant Nephroureterectomy and Native Cystectomy
title_full Second Renal Transplantation With Simultaneous Ileal Conduit Creation Following Transplant Nephroureterectomy and Native Cystectomy
title_fullStr Second Renal Transplantation With Simultaneous Ileal Conduit Creation Following Transplant Nephroureterectomy and Native Cystectomy
title_full_unstemmed Second Renal Transplantation With Simultaneous Ileal Conduit Creation Following Transplant Nephroureterectomy and Native Cystectomy
title_short Second Renal Transplantation With Simultaneous Ileal Conduit Creation Following Transplant Nephroureterectomy and Native Cystectomy
title_sort second renal transplantation with simultaneous ileal conduit creation following transplant nephroureterectomy and native cystectomy
topic BK virus
ileal conduit
second renal transplantation
urothelial carcinoma
url https://doi.org/10.1002/iju5.70044
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AT takehiroohyama secondrenaltransplantationwithsimultaneousilealconduitcreationfollowingtransplantnephroureterectomyandnativecystectomy
AT kyokominamisono secondrenaltransplantationwithsimultaneousilealconduitcreationfollowingtransplantnephroureterectomyandnativecystectomy
AT shonishida secondrenaltransplantationwithsimultaneousilealconduitcreationfollowingtransplantnephroureterectomyandnativecystectomy
AT daikiiwami secondrenaltransplantationwithsimultaneousilealconduitcreationfollowingtransplantnephroureterectomyandnativecystectomy