Design, Synthesis, Structural Insights, Tyrosinase Inhibition, and Sun Protection Factor of New Thiosemicarbazone Derivatives

Design, Synthesis, Structural Insights, Tyrosinase Inhibition, and Sun Protection Factor of New Thiosemicarbazone Derivatives

Tyrosinase, a key protein in the biosynthesis of melanin pigments, is crucial in determining skin pigmentation. Inhibiting tyrosinase activity is a promising approach for treating conditions related to excessive pigmentation. For the synthesis of more potent tyrosinase inhibitors, we combined two ap...

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Bibliographic Details
Main Authors: Sebastiano Masuri, Benedetta Era, Francesca Pintus, Sonia Floris, Francesca Meloni, Francesca Pettinau, Enrico Podda, Maria Grazia Cabiddu, Antonella Fais, Tiziana Pivetta
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Molecules
Subjects:
thiosemicarbazones
tyrosinase
enzyme inhibition
Online Access:https://www.mdpi.com/1420-3049/29/23/5629
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