Dose-dependent serological profiling of AdCLD-CoV19-1 vaccine in adults

Dose-dependent serological profiling of AdCLD-CoV19-1 vaccine in adults

ABSTRACT AdCLD-CoV19-1, a chimeric adenovirus-based severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine, was previously reported to elicit robust antibody responses in mice and non-human primates after a single dose. In this study, we conducted a systems serology analysis to investi...

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Main Authors: Jung Hyuk Lee, Yuna Shin, Kwang-Soo Shin, Ju Yeon Park, Mi Sun Kim, Young-Shin Park, Wuhyun Kim, Joon Young Song, Ji Yun Noh, Hee Jin Cheong, Chang-Yuil Kang, Sang Hwan Seo, Jae-Ouk Kim, Deok Ryun Kim, Nathaniel S. Hwang, Jae Seung Yang, Jerome H. Kim, Byoung-Shik Shim, Manki Song
Format: Article
Language:English
Published: American Society for Microbiology 2025-01-01
Series:mSphere
Subjects:
systems serology
SARS-CoV-2
adenovirus vector-based vaccine
effector function
spike protein
Online Access:https://journals.asm.org/doi/10.1128/msphere.00998-24
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