Prevalence and factors associated with low medication adherence among Type 2 Diabetic patients attending a diabetic clinic at the Tema general hospital, Ghana

Introduction: Poor adherence to diabetes medication has been linked to poor glycemic control, increased cost, morbidity, and mortality rates. This study assessed factors influencing adherence to medication regimens among outpatients with type 2 diabetes mellitus (T2DM) patients at a diabetes clinic...

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Main Authors: Perpetual Enam Aflakpui, Delia Akosua Benewah Bandoh, Emma Edinam Kploanyi, Ernest Kenu, Adolphina Addoley Addo-Lartey
Format: Article
Language:English
Published: African Field Epidemiology Network 2022-04-01
Series:Journal of Interventional Epidemiology and Public Health
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Online Access:https://www.afenet-journal.net/content/article/5/4/full/
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author Perpetual Enam Aflakpui
Delia Akosua Benewah Bandoh
Emma Edinam Kploanyi
Ernest Kenu
Adolphina Addoley Addo-Lartey
author_facet Perpetual Enam Aflakpui
Delia Akosua Benewah Bandoh
Emma Edinam Kploanyi
Ernest Kenu
Adolphina Addoley Addo-Lartey
author_sort Perpetual Enam Aflakpui
collection DOAJ
description Introduction: Poor adherence to diabetes medication has been linked to poor glycemic control, increased cost, morbidity, and mortality rates. This study assessed factors influencing adherence to medication regimens among outpatients with type 2 diabetes mellitus (T2DM) patients at a diabetes clinic, Tema General Hospital, Ghana. Methods: This was a cross-sectional study using quantitative methods. A culturally tailored semi-structured questionnaire and the Morisky Medication Adherence Scale (MMAS-8) were used to evaluate the levels of adherence to T2DM medications. Chi-square test and logistic regression were used to assess the association between exposure variables and medication adherence. Results: A total of 206 T2DM patients aged 24 to 90 years, mean age=59.1(±1) years were interviewed. The majority were female (82.5%) and married (56.8%). The prevalence of low adherence to T2DM medication was 47.6% (95%CI: 0.41-0.55). Respondents who were on herbal medication (AOR: 5.99; 95%CI= (0.21–71.65)) had the lowest adherence compared to those on insulin followed by Insulin +OHA (AOR; 95%CI=3.15(0.79-12.53)) and OHA medication (AOR: 1.24; 95%CI (0.42-3.68)). Among those who reported side effects from medication, the odds of low adherence was 2.9 times compared to those who did not report any (AOR;95%CI=2.91(1.16-7.29)). Those who reported that their pill burden affected the continued usage of medication had 8.3 times the odds of low adherence compared to those who did not (AOR; 95%CI=8.25 (2.95-23.08)). Irregular visits to the health facility (AOR; 95%CI=6.71(2.35-19.16)) and the provision of information on the disease condition by the health provider (AOR; 95%CI= 1.14 (0.15-8.75)) significantly influenced adherence to the medication regimen. Conclusion: The prevalence of low adherence to the T2DM medication regimen was influenced by current medication intake, experiencing side effects from medication, pill burden, irregular visits to the health facility, and adequacy of information provided by health providers on the disease condition. National level interventions are needed to intensify health education on diabetes management.
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spelling doaj-art-e070ff419c204b13b33811e3deeee7de2025-08-20T03:13:07ZengAfrican Field Epidemiology NetworkJournal of Interventional Epidemiology and Public Health2664-28242022-04-0152https://doi.org/10.37432/jieph.2022.5.2.52Prevalence and factors associated with low medication adherence among Type 2 Diabetic patients attending a diabetic clinic at the Tema general hospital, GhanaPerpetual Enam Aflakpui0Delia Akosua Benewah Bandoh1Emma Edinam Kploanyi2Ernest Kenu3Adolphina Addoley Addo-Lartey4Department of Epidemiology and Disease Control, School of Public Health, University of Ghana, Legon, Accra, GhanaGFELTP, Department of Epidemiology and Disease Control, School of Public Health, University of Ghana, Legon, Accra, GhanaGFELTP, Department of Epidemiology and Disease Control, School of Public Health, University of Ghana, Legon, Accra, GhanaGFELTP, Department of Epidemiology and Disease Control, School of Public Health, University of Ghana, Legon, Accra, GhanaDepartment of Epidemiology and Disease Control, School of Public Health, University of Ghana, Legon, Accra, Ghana Introduction: Poor adherence to diabetes medication has been linked to poor glycemic control, increased cost, morbidity, and mortality rates. This study assessed factors influencing adherence to medication regimens among outpatients with type 2 diabetes mellitus (T2DM) patients at a diabetes clinic, Tema General Hospital, Ghana. Methods: This was a cross-sectional study using quantitative methods. A culturally tailored semi-structured questionnaire and the Morisky Medication Adherence Scale (MMAS-8) were used to evaluate the levels of adherence to T2DM medications. Chi-square test and logistic regression were used to assess the association between exposure variables and medication adherence. Results: A total of 206 T2DM patients aged 24 to 90 years, mean age=59.1(±1) years were interviewed. The majority were female (82.5%) and married (56.8%). The prevalence of low adherence to T2DM medication was 47.6% (95%CI: 0.41-0.55). Respondents who were on herbal medication (AOR: 5.99; 95%CI= (0.21–71.65)) had the lowest adherence compared to those on insulin followed by Insulin +OHA (AOR; 95%CI=3.15(0.79-12.53)) and OHA medication (AOR: 1.24; 95%CI (0.42-3.68)). Among those who reported side effects from medication, the odds of low adherence was 2.9 times compared to those who did not report any (AOR;95%CI=2.91(1.16-7.29)). Those who reported that their pill burden affected the continued usage of medication had 8.3 times the odds of low adherence compared to those who did not (AOR; 95%CI=8.25 (2.95-23.08)). Irregular visits to the health facility (AOR; 95%CI=6.71(2.35-19.16)) and the provision of information on the disease condition by the health provider (AOR; 95%CI= 1.14 (0.15-8.75)) significantly influenced adherence to the medication regimen. Conclusion: The prevalence of low adherence to the T2DM medication regimen was influenced by current medication intake, experiencing side effects from medication, pill burden, irregular visits to the health facility, and adequacy of information provided by health providers on the disease condition. National level interventions are needed to intensify health education on diabetes management.https://www.afenet-journal.net/content/article/5/4/full/tupe 2 diabetis mellitusadherencemedicationglycemic controlghana
spellingShingle Perpetual Enam Aflakpui
Delia Akosua Benewah Bandoh
Emma Edinam Kploanyi
Ernest Kenu
Adolphina Addoley Addo-Lartey
Prevalence and factors associated with low medication adherence among Type 2 Diabetic patients attending a diabetic clinic at the Tema general hospital, Ghana
Journal of Interventional Epidemiology and Public Health
tupe 2 diabetis mellitus
adherence
medication
glycemic control
ghana
title Prevalence and factors associated with low medication adherence among Type 2 Diabetic patients attending a diabetic clinic at the Tema general hospital, Ghana
title_full Prevalence and factors associated with low medication adherence among Type 2 Diabetic patients attending a diabetic clinic at the Tema general hospital, Ghana
title_fullStr Prevalence and factors associated with low medication adherence among Type 2 Diabetic patients attending a diabetic clinic at the Tema general hospital, Ghana
title_full_unstemmed Prevalence and factors associated with low medication adherence among Type 2 Diabetic patients attending a diabetic clinic at the Tema general hospital, Ghana
title_short Prevalence and factors associated with low medication adherence among Type 2 Diabetic patients attending a diabetic clinic at the Tema general hospital, Ghana
title_sort prevalence and factors associated with low medication adherence among type 2 diabetic patients attending a diabetic clinic at the tema general hospital ghana
topic tupe 2 diabetis mellitus
adherence
medication
glycemic control
ghana
url https://www.afenet-journal.net/content/article/5/4/full/
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