Global burden of low back pain and its attributable risk factors from 1990 to 2021: a comprehensive analysis from the global burden of disease study 2021
BackgroundThis study aimed to examine the evolving trends in the global burden of low back pain (LBP) from 1990 to 2021 and predicted disease burden until 2035.Materials and methodsLBP-related data were obtained from the Global Health Data Exchange (GHDx) query tool. All estimates and their 95% unce...
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Frontiers Media S.A.
2024-11-01
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author | Yue Li Congying Zou Weidong Guo Feng Han Tao Fan Lei Zang Guoshun Huang |
author_facet | Yue Li Congying Zou Weidong Guo Feng Han Tao Fan Lei Zang Guoshun Huang |
author_sort | Yue Li |
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description | BackgroundThis study aimed to examine the evolving trends in the global burden of low back pain (LBP) from 1990 to 2021 and predicted disease burden until 2035.Materials and methodsLBP-related data were obtained from the Global Health Data Exchange (GHDx) query tool. All estimates and their 95% uncertainty intervals (UIs) were generated using DisMod-MR 2.1, a Bayesian meta-regression tool in Global Burden of Disease, Injury, and Risk Factor Study (GBD) 2021. Data processing and visualization were conducted using The R Programming Language software version 4.3.2 and Joinpoint 4.7.ResultsIn 2021, approximately 628.8 million people worldwide were affected by LBP, with approximately 266.9 million new incident cases and age-standardized incidence rate (ASIR) of 3176.6 per 100,000. Compared with 1990, although the ASIR and age-standardized disability-adjusted life years rate (ASDALYsR) decreased, absolute numbers increased significantly. Projections for 2035 reveal a continued decline in ASIR and ASDALYsR for LBP. The LBP burden varied by the sociodemographic index quintile and GBD region, with the highest ASIR and ASDALYsR observed in Central Europe and the greatest decrease in East Asia. Globally, women bear a higher burden of LBP than men, with middle-aged populations experiencing the heaviest burden. Occupational ergonomic factors, high body mass index, and smoking remain the primary risk factors for LBP, with occupational ergonomic factors contributing the most to the overall burden.ConclusionDespite a projected decline in incidence, the global burden of LBP persists, exhibiting significant regional and gender disparities. To mitigate its future burden, precise and effective prevention and control strategies targeting high-risk factors are imperative. |
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language | English |
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spelling | doaj-art-e06d0a0595b147e098fcb4f2d32aaf3c2024-11-13T05:10:22ZengFrontiers Media S.A.Frontiers in Public Health2296-25652024-11-011210.3389/fpubh.2024.14807791480779Global burden of low back pain and its attributable risk factors from 1990 to 2021: a comprehensive analysis from the global burden of disease study 2021Yue Li0Congying Zou1Weidong Guo2Feng Han3Tao Fan4Lei Zang5Guoshun Huang6Department of Orthopedic Surgery, General Hospital of Tisco, Taiyuan, Shanxi, ChinaDepartment of Orthopedic Surgery, Beijing Chao-yang Hospital, Capital Medical University, Beijing, ChinaDepartment of Orthopedic Surgery, General Hospital of Tisco, Taiyuan, Shanxi, ChinaDepartment of Orthopedic Surgery, General Hospital of Tisco, Taiyuan, Shanxi, ChinaDepartment of Orthopedic Surgery, General Hospital of Tisco, Taiyuan, Shanxi, ChinaDepartment of Orthopedic Surgery, Beijing Chao-yang Hospital, Capital Medical University, Beijing, ChinaDepartment of Orthopedic Surgery, General Hospital of Tisco, Taiyuan, Shanxi, ChinaBackgroundThis study aimed to examine the evolving trends in the global burden of low back pain (LBP) from 1990 to 2021 and predicted disease burden until 2035.Materials and methodsLBP-related data were obtained from the Global Health Data Exchange (GHDx) query tool. All estimates and their 95% uncertainty intervals (UIs) were generated using DisMod-MR 2.1, a Bayesian meta-regression tool in Global Burden of Disease, Injury, and Risk Factor Study (GBD) 2021. Data processing and visualization were conducted using The R Programming Language software version 4.3.2 and Joinpoint 4.7.ResultsIn 2021, approximately 628.8 million people worldwide were affected by LBP, with approximately 266.9 million new incident cases and age-standardized incidence rate (ASIR) of 3176.6 per 100,000. Compared with 1990, although the ASIR and age-standardized disability-adjusted life years rate (ASDALYsR) decreased, absolute numbers increased significantly. Projections for 2035 reveal a continued decline in ASIR and ASDALYsR for LBP. The LBP burden varied by the sociodemographic index quintile and GBD region, with the highest ASIR and ASDALYsR observed in Central Europe and the greatest decrease in East Asia. Globally, women bear a higher burden of LBP than men, with middle-aged populations experiencing the heaviest burden. Occupational ergonomic factors, high body mass index, and smoking remain the primary risk factors for LBP, with occupational ergonomic factors contributing the most to the overall burden.ConclusionDespite a projected decline in incidence, the global burden of LBP persists, exhibiting significant regional and gender disparities. To mitigate its future burden, precise and effective prevention and control strategies targeting high-risk factors are imperative.https://www.frontiersin.org/articles/10.3389/fpubh.2024.1480779/fulllow back painglobal burden of diseaseage-standardized incidence rateage-standardized disability-adjusted life years raterisk factors |
spellingShingle | Yue Li Congying Zou Weidong Guo Feng Han Tao Fan Lei Zang Guoshun Huang Global burden of low back pain and its attributable risk factors from 1990 to 2021: a comprehensive analysis from the global burden of disease study 2021 Frontiers in Public Health low back pain global burden of disease age-standardized incidence rate age-standardized disability-adjusted life years rate risk factors |
title | Global burden of low back pain and its attributable risk factors from 1990 to 2021: a comprehensive analysis from the global burden of disease study 2021 |
title_full | Global burden of low back pain and its attributable risk factors from 1990 to 2021: a comprehensive analysis from the global burden of disease study 2021 |
title_fullStr | Global burden of low back pain and its attributable risk factors from 1990 to 2021: a comprehensive analysis from the global burden of disease study 2021 |
title_full_unstemmed | Global burden of low back pain and its attributable risk factors from 1990 to 2021: a comprehensive analysis from the global burden of disease study 2021 |
title_short | Global burden of low back pain and its attributable risk factors from 1990 to 2021: a comprehensive analysis from the global burden of disease study 2021 |
title_sort | global burden of low back pain and its attributable risk factors from 1990 to 2021 a comprehensive analysis from the global burden of disease study 2021 |
topic | low back pain global burden of disease age-standardized incidence rate age-standardized disability-adjusted life years rate risk factors |
url | https://www.frontiersin.org/articles/10.3389/fpubh.2024.1480779/full |
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