Primary Isolated Lymphoma of the Fourth Ventricle in an Immunocompetent Patient
Primary central nervous lymphoma (PCNSL) is a rare variant of extranodal non-Hodgkin's lymphoma with a especially poor prognosis. The diagnosis is usually encountered in immunodeficient patients but is also encountered, albeit uncommonly, in the immunocompetent. We present a 50-year-old male wh...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Case Reports in Oncological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2013/614658 |
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| author | Rakan Bokhari Ahmad Ghanem Mahmoud Alahwal Saleh Baeesa |
| author_facet | Rakan Bokhari Ahmad Ghanem Mahmoud Alahwal Saleh Baeesa |
| author_sort | Rakan Bokhari |
| collection | DOAJ |
| description | Primary central nervous lymphoma (PCNSL) is a rare variant of extranodal non-Hodgkin's lymphoma with a especially poor prognosis. The diagnosis is usually encountered in immunodeficient patients but is also encountered, albeit uncommonly, in the immunocompetent. We present a 50-year-old male who developed signs and symptoms of increased intracranial pressure. Imaging revealed the presence of a fourth ventricle mass with obstructive hydrocephalus. First, the patient underwent emergency endoscopic third ventriculostomy followed, few days later, by complete tumor resection via a posterior fossa craniotomy. Postoperative histopathology revealed the lesion to be a PCNSL. He received adjuvant chemotherapy and radiation and remained with no recurrence on regular imaging studies for 18-month followup. We report herein the fourth case of isolated PCNSL lesion to the fourth ventricle in the literature and provide the rationale for our belief that craniotomy and tumor resection, if feasible, should be the initial line of management in similar cases to relieve hydrocephalus and achieve the diagnosis. |
| format | Article |
| id | doaj-art-e06d00d001a943ee8bc7ff9df7a2c5ea |
| institution | Kabale University |
| issn | 2090-6706 2090-6714 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Oncological Medicine |
| spelling | doaj-art-e06d00d001a943ee8bc7ff9df7a2c5ea2025-02-03T06:11:33ZengWileyCase Reports in Oncological Medicine2090-67062090-67142013-01-01201310.1155/2013/614658614658Primary Isolated Lymphoma of the Fourth Ventricle in an Immunocompetent PatientRakan Bokhari0Ahmad Ghanem1Mahmoud Alahwal2Saleh Baeesa3Division of Neurological Surgery, Faculty of Medicine, King Abdulaziz University, P.O. Box 80215, Jeddah 21589, Saudi ArabiaDepartment of Pathology, Faculty of Medicine, King Abdulaziz University, P.O. Box 80215, Jeddah 21589, Saudi ArabiaDepartment of Medicine, Faculty of Medicine, King Abdulaziz University, P.O. Box 80215, Jeddah 21589, Saudi ArabiaDivision of Neurological Surgery, Faculty of Medicine, King Abdulaziz University, P.O. Box 80215, Jeddah 21589, Saudi ArabiaPrimary central nervous lymphoma (PCNSL) is a rare variant of extranodal non-Hodgkin's lymphoma with a especially poor prognosis. The diagnosis is usually encountered in immunodeficient patients but is also encountered, albeit uncommonly, in the immunocompetent. We present a 50-year-old male who developed signs and symptoms of increased intracranial pressure. Imaging revealed the presence of a fourth ventricle mass with obstructive hydrocephalus. First, the patient underwent emergency endoscopic third ventriculostomy followed, few days later, by complete tumor resection via a posterior fossa craniotomy. Postoperative histopathology revealed the lesion to be a PCNSL. He received adjuvant chemotherapy and radiation and remained with no recurrence on regular imaging studies for 18-month followup. We report herein the fourth case of isolated PCNSL lesion to the fourth ventricle in the literature and provide the rationale for our belief that craniotomy and tumor resection, if feasible, should be the initial line of management in similar cases to relieve hydrocephalus and achieve the diagnosis.http://dx.doi.org/10.1155/2013/614658 |
| spellingShingle | Rakan Bokhari Ahmad Ghanem Mahmoud Alahwal Saleh Baeesa Primary Isolated Lymphoma of the Fourth Ventricle in an Immunocompetent Patient Case Reports in Oncological Medicine |
| title | Primary Isolated Lymphoma of the Fourth Ventricle in an Immunocompetent Patient |
| title_full | Primary Isolated Lymphoma of the Fourth Ventricle in an Immunocompetent Patient |
| title_fullStr | Primary Isolated Lymphoma of the Fourth Ventricle in an Immunocompetent Patient |
| title_full_unstemmed | Primary Isolated Lymphoma of the Fourth Ventricle in an Immunocompetent Patient |
| title_short | Primary Isolated Lymphoma of the Fourth Ventricle in an Immunocompetent Patient |
| title_sort | primary isolated lymphoma of the fourth ventricle in an immunocompetent patient |
| url | http://dx.doi.org/10.1155/2013/614658 |
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