Intravesical BCG therapy-induced granulomatous prostatitis in a patient with non-muscle invasive bladder cancer and prostate adenocarcinoma
Granulomatous prostatitis (GP) is a rare inflammatory condition that may mimic prostate cancer (PC) progression. We present the case of a 64-year-old man with low-risk PC on active surveillance who developed Bacillus Calmette-Guérin (BCG)-induced GP following intravesical therapy for non-muscle inva...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-05-01
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| Series: | Urology Case Reports |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2214442025000919 |
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| author | Ryan Yu Qian (Janie) Qin George K. Haines William K. Oh Sara Lewis |
| author_facet | Ryan Yu Qian (Janie) Qin George K. Haines William K. Oh Sara Lewis |
| author_sort | Ryan Yu |
| collection | DOAJ |
| description | Granulomatous prostatitis (GP) is a rare inflammatory condition that may mimic prostate cancer (PC) progression. We present the case of a 64-year-old man with low-risk PC on active surveillance who developed Bacillus Calmette-Guérin (BCG)-induced GP following intravesical therapy for non-muscle invasive bladder cancer. Clinical and imaging findings suggested PC progression, but biopsy confirmed granulomatous inflammation without malignancy upstaging. This case underscores the similarities in clinical presentation, as well as the importance of histopathological evaluation in differentiating GP from PC. |
| format | Article |
| id | doaj-art-e06cbd654b5143b7b2cd1a2f7bdb76da |
| institution | DOAJ |
| issn | 2214-4420 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Urology Case Reports |
| spelling | doaj-art-e06cbd654b5143b7b2cd1a2f7bdb76da2025-08-20T03:14:17ZengElsevierUrology Case Reports2214-44202025-05-016010302010.1016/j.eucr.2025.103020Intravesical BCG therapy-induced granulomatous prostatitis in a patient with non-muscle invasive bladder cancer and prostate adenocarcinomaRyan Yu0Qian (Janie) Qin1George K. Haines2William K. Oh3Sara Lewis4Icahn School of Medicine at Mount Sinai, New York, NY, USA; Corresponding author. Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Pl, New York, NY, 10029, USA.Department of Medicine, Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai, New York, NY, USADepartment of Anatomic Pathology and Clinical Pathology, Icahn School of Medicine at Mount Sinai, New York, NY, USADepartment of Medicine, Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai, New York, NY, USADepartment of Diagnostic, Interventional and Molecular Imaging, Icahn School of Medicine at Mount Sinai, New York, NY, USAGranulomatous prostatitis (GP) is a rare inflammatory condition that may mimic prostate cancer (PC) progression. We present the case of a 64-year-old man with low-risk PC on active surveillance who developed Bacillus Calmette-Guérin (BCG)-induced GP following intravesical therapy for non-muscle invasive bladder cancer. Clinical and imaging findings suggested PC progression, but biopsy confirmed granulomatous inflammation without malignancy upstaging. This case underscores the similarities in clinical presentation, as well as the importance of histopathological evaluation in differentiating GP from PC.http://www.sciencedirect.com/science/article/pii/S2214442025000919 |
| spellingShingle | Ryan Yu Qian (Janie) Qin George K. Haines William K. Oh Sara Lewis Intravesical BCG therapy-induced granulomatous prostatitis in a patient with non-muscle invasive bladder cancer and prostate adenocarcinoma Urology Case Reports |
| title | Intravesical BCG therapy-induced granulomatous prostatitis in a patient with non-muscle invasive bladder cancer and prostate adenocarcinoma |
| title_full | Intravesical BCG therapy-induced granulomatous prostatitis in a patient with non-muscle invasive bladder cancer and prostate adenocarcinoma |
| title_fullStr | Intravesical BCG therapy-induced granulomatous prostatitis in a patient with non-muscle invasive bladder cancer and prostate adenocarcinoma |
| title_full_unstemmed | Intravesical BCG therapy-induced granulomatous prostatitis in a patient with non-muscle invasive bladder cancer and prostate adenocarcinoma |
| title_short | Intravesical BCG therapy-induced granulomatous prostatitis in a patient with non-muscle invasive bladder cancer and prostate adenocarcinoma |
| title_sort | intravesical bcg therapy induced granulomatous prostatitis in a patient with non muscle invasive bladder cancer and prostate adenocarcinoma |
| url | http://www.sciencedirect.com/science/article/pii/S2214442025000919 |
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