Limosilactobacillus reuteri - a probiotic gut commensal with contextual impact on immunity
The gut microbiome plays a key role in human health, influencing various biological processes and disease outcomes. The historical roots of probiotics are traced back to Nobel Laureate Élie Metchnikoff, who linked the longevity of Bulgarian villagers to their consumption of sour milk fermented by La...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2025-12-01
|
| Series: | Gut Microbes |
| Subjects: | |
| Online Access: | https://www.tandfonline.com/doi/10.1080/19490976.2025.2451088 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832595717155192832 |
|---|---|
| author | Amanda H. Lee Daphne Michelle Rodriguez Jimenez Marlies Meisel |
| author_facet | Amanda H. Lee Daphne Michelle Rodriguez Jimenez Marlies Meisel |
| author_sort | Amanda H. Lee |
| collection | DOAJ |
| description | The gut microbiome plays a key role in human health, influencing various biological processes and disease outcomes. The historical roots of probiotics are traced back to Nobel Laureate Élie Metchnikoff, who linked the longevity of Bulgarian villagers to their consumption of sour milk fermented by Lactobacilli. His pioneering work led to the global recognition of probiotics as beneficial supplements, now a multibillion-dollar industry. Modern probiotics have been extensively studied for their immunomodulatory effects. Limosilactobacillus reuteri (L. reuteri), a widely used probiotic, has garnered significant attention for its systemic immune-regulatory properties, particularly in relation to autoimmunity and cancer. This review delves into the role of L. reuteri in modulating immune responses, with a focus on its impact on systemic diseases. |
| format | Article |
| id | doaj-art-e06c68a858e64aa599de06272b1212fe |
| institution | Kabale University |
| issn | 1949-0976 1949-0984 |
| language | English |
| publishDate | 2025-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Gut Microbes |
| spelling | doaj-art-e06c68a858e64aa599de06272b1212fe2025-01-18T07:52:50ZengTaylor & Francis GroupGut Microbes1949-09761949-09842025-12-0117110.1080/19490976.2025.2451088Limosilactobacillus reuteri - a probiotic gut commensal with contextual impact on immunityAmanda H. Lee0Daphne Michelle Rodriguez Jimenez1Marlies Meisel2Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USADepartment of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USADepartment of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USAThe gut microbiome plays a key role in human health, influencing various biological processes and disease outcomes. The historical roots of probiotics are traced back to Nobel Laureate Élie Metchnikoff, who linked the longevity of Bulgarian villagers to their consumption of sour milk fermented by Lactobacilli. His pioneering work led to the global recognition of probiotics as beneficial supplements, now a multibillion-dollar industry. Modern probiotics have been extensively studied for their immunomodulatory effects. Limosilactobacillus reuteri (L. reuteri), a widely used probiotic, has garnered significant attention for its systemic immune-regulatory properties, particularly in relation to autoimmunity and cancer. This review delves into the role of L. reuteri in modulating immune responses, with a focus on its impact on systemic diseases.https://www.tandfonline.com/doi/10.1080/19490976.2025.2451088Autoimmunitycancerimmune systemLimosilactobacillus reuteriprobioticsystemic disease |
| spellingShingle | Amanda H. Lee Daphne Michelle Rodriguez Jimenez Marlies Meisel Limosilactobacillus reuteri - a probiotic gut commensal with contextual impact on immunity Gut Microbes Autoimmunity cancer immune system Limosilactobacillus reuteri probiotic systemic disease |
| title | Limosilactobacillus reuteri - a probiotic gut commensal with contextual impact on immunity |
| title_full | Limosilactobacillus reuteri - a probiotic gut commensal with contextual impact on immunity |
| title_fullStr | Limosilactobacillus reuteri - a probiotic gut commensal with contextual impact on immunity |
| title_full_unstemmed | Limosilactobacillus reuteri - a probiotic gut commensal with contextual impact on immunity |
| title_short | Limosilactobacillus reuteri - a probiotic gut commensal with contextual impact on immunity |
| title_sort | limosilactobacillus reuteri a probiotic gut commensal with contextual impact on immunity |
| topic | Autoimmunity cancer immune system Limosilactobacillus reuteri probiotic systemic disease |
| url | https://www.tandfonline.com/doi/10.1080/19490976.2025.2451088 |
| work_keys_str_mv | AT amandahlee limosilactobacillusreuteriaprobioticgutcommensalwithcontextualimpactonimmunity AT daphnemichellerodriguezjimenez limosilactobacillusreuteriaprobioticgutcommensalwithcontextualimpactonimmunity AT marliesmeisel limosilactobacillusreuteriaprobioticgutcommensalwithcontextualimpactonimmunity |