Research advances of extracellular vesicles in lung diseases
The lung is a vital organ in the respiratory system, and there is a critical need to develop more effective methods for lung health management. Extracellular vesicles (EVs) play an important role in intercellular communication. They exhibit high bioavailability and low immunogenicity, making them es...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2025-08-01
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| Series: | Cell Transplantation |
| Online Access: | https://doi.org/10.1177/09636897251362031 |
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| _version_ | 1849236268758597632 |
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| author | Jian Wang Yaning Shi Yuehan Su Chaoyue Pang Yimiao Yang Weiwei Wang |
| author_facet | Jian Wang Yaning Shi Yuehan Su Chaoyue Pang Yimiao Yang Weiwei Wang |
| author_sort | Jian Wang |
| collection | DOAJ |
| description | The lung is a vital organ in the respiratory system, and there is a critical need to develop more effective methods for lung health management. Extracellular vesicles (EVs) play an important role in intercellular communication. They exhibit high bioavailability and low immunogenicity, making them essential in maintaining cellular homeostasis and in the prevention and treatment of numerous diseases. This review describes the diverse sources, isolation techniques, functions, and challenges associated with EVs, particularly exosomes. We highlight their significant role in the diagnosis and treatment of lung diseases, as well as their potential as drug delivery vehicles. By synthesizing recent advances in EVs research, this review aims to provide a theoretical foundation for future studies and clinical applications of EVs. |
| format | Article |
| id | doaj-art-e05b63c12fe14bd28ee55fd06165ffa5 |
| institution | Kabale University |
| issn | 1555-3892 |
| language | English |
| publishDate | 2025-08-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Cell Transplantation |
| spelling | doaj-art-e05b63c12fe14bd28ee55fd06165ffa52025-08-20T04:02:22ZengSAGE PublishingCell Transplantation1555-38922025-08-013410.1177/09636897251362031Research advances of extracellular vesicles in lung diseasesJian Wang0Yaning Shi1Yuehan Su2Chaoyue Pang3Yimiao Yang4Weiwei Wang5Oriental Beauty Valley Institute of Regenerative Medicine, Shanghai, ChinaOriental Beauty Valley Institute of Regenerative Medicine, Shanghai, ChinaANEXT Shanghai Biotechnology Co., Ltd., Shanghai, ChinaANEXT Shanghai Biotechnology Co., Ltd., Shanghai, ChinaANEXT Shanghai Biotechnology Co., Ltd., Shanghai, ChinaOriental Beauty Valley Institute of Regenerative Medicine, Shanghai, ChinaThe lung is a vital organ in the respiratory system, and there is a critical need to develop more effective methods for lung health management. Extracellular vesicles (EVs) play an important role in intercellular communication. They exhibit high bioavailability and low immunogenicity, making them essential in maintaining cellular homeostasis and in the prevention and treatment of numerous diseases. This review describes the diverse sources, isolation techniques, functions, and challenges associated with EVs, particularly exosomes. We highlight their significant role in the diagnosis and treatment of lung diseases, as well as their potential as drug delivery vehicles. By synthesizing recent advances in EVs research, this review aims to provide a theoretical foundation for future studies and clinical applications of EVs.https://doi.org/10.1177/09636897251362031 |
| spellingShingle | Jian Wang Yaning Shi Yuehan Su Chaoyue Pang Yimiao Yang Weiwei Wang Research advances of extracellular vesicles in lung diseases Cell Transplantation |
| title | Research advances of extracellular vesicles in lung diseases |
| title_full | Research advances of extracellular vesicles in lung diseases |
| title_fullStr | Research advances of extracellular vesicles in lung diseases |
| title_full_unstemmed | Research advances of extracellular vesicles in lung diseases |
| title_short | Research advances of extracellular vesicles in lung diseases |
| title_sort | research advances of extracellular vesicles in lung diseases |
| url | https://doi.org/10.1177/09636897251362031 |
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