Modulation of phosphatase of regenerating liver-1 within placental mesenchymal stem cells instigates the transition between epithelial-to-mesenchymal transition and mesenchymal-to-epithelial transition subsequent to hepatic fibrosis

Modulation of phosphatase of regenerating liver-1 within placental mesenchymal stem cells instigates the transition between epithelial-to-mesenchymal transition and mesenchymal-to-epithelial transition subsequent to hepatic fibrosis

Background/Aims Epithelial-to-mesenchymal transition (EMT) plays a crucial role in hepatic fibrogenesis and liver repair in chronic liver disease. Our research highlights the antifibrotic potential of placenta-derived mesenchymal stem cells (PD-MSCs) and the role of phosphatase of regenerating liver...

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Bibliographic Details
Main Authors: Jae Yeon Kim, Hyeri Park, Soo Young Park, Se Ho Kim, Ja Yun Lim, Ki Seog Lee, Si Hyun Bae, Gi Jin Kim
Format: Article
Language:English
Published: Korean Association for the Study of the Liver 2025-07-01
Series:Clinical and Molecular Hepatology
Subjects:
epithelial-mesenchymal transition
liver diseases
mesenchymal stem cell transplantation
protein tyrosine phosphatases
Online Access:http://e-cmh.org/upload/pdf/cmh-2024-0741.pdf
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