Determination of MDA as oxidative stress marker and most common type of blood group in asthmatic patients before and after treatment with montelukast drug.

Asthma is a complex chronic inflammatory disorder of airways characterized by airway smooth muscle hypertrophy, hyperplasia and over production of mucous in which many cells and cellular elements play an important role. The aim of the study is to monitor the changes in asthmatic patients before...

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Main Authors: Jwad Ali Saleh, Shakir Mahmoud Suleiman, Zaidan Jayed Zaidan
Format: Article
Language:English
Published: Tikrit University 2023-02-01
Series:Tikrit Journal of Pure Science
Subjects:
Online Access:https://tjpsj.org/index.php/tjps/article/view/1164
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author Jwad Ali Saleh
Shakir Mahmoud Suleiman
Zaidan Jayed Zaidan
author_facet Jwad Ali Saleh
Shakir Mahmoud Suleiman
Zaidan Jayed Zaidan
author_sort Jwad Ali Saleh
collection DOAJ
description Asthma is a complex chronic inflammatory disorder of airways characterized by airway smooth muscle hypertrophy, hyperplasia and over production of mucous in which many cells and cellular elements play an important role. The aim of the study is to monitor the changes in asthmatic patients before and after treatment with montelukast in the MDA level as oxidative stress marker in asthmatic cases, and the most common type of blood group. The total number of subjects included in this study was two hundred with acute asthma. The major part of this study represents a follow up study. Subjects with bronchial asthma were previously diagnosed but not on regular treatment, their aged ranged between (16 – 50) years attending the respiratory unit directly at tikrit teaching hospital. The period of data collection was from first of April of 2013 up to the mid of June- 2014.  There is a significant change in level of MDA, during the asthmatic attacks (1.12± 0.42, while after treatment (0.6 ± 0.34 P ≤ 0.001). The most common type of blood group in asthmatic cases is type O which about 69% from total number of cases , type A about 18.5%, type B about 9% , and type AB about 3.5%).
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spelling doaj-art-e04efed9a752473684bbc722c6b7b6eb2025-08-20T03:17:48ZengTikrit UniversityTikrit Journal of Pure Science1813-16622415-17262023-02-0120210.25130/tjps.v20i2.1164Determination of MDA as oxidative stress marker and most common type of blood group in asthmatic patients before and after treatment with montelukast drug.Jwad Ali SalehShakir Mahmoud SuleimanZaidan Jayed Zaidan Asthma is a complex chronic inflammatory disorder of airways characterized by airway smooth muscle hypertrophy, hyperplasia and over production of mucous in which many cells and cellular elements play an important role. The aim of the study is to monitor the changes in asthmatic patients before and after treatment with montelukast in the MDA level as oxidative stress marker in asthmatic cases, and the most common type of blood group. The total number of subjects included in this study was two hundred with acute asthma. The major part of this study represents a follow up study. Subjects with bronchial asthma were previously diagnosed but not on regular treatment, their aged ranged between (16 – 50) years attending the respiratory unit directly at tikrit teaching hospital. The period of data collection was from first of April of 2013 up to the mid of June- 2014.  There is a significant change in level of MDA, during the asthmatic attacks (1.12± 0.42, while after treatment (0.6 ± 0.34 P ≤ 0.001). The most common type of blood group in asthmatic cases is type O which about 69% from total number of cases , type A about 18.5%, type B about 9% , and type AB about 3.5%). https://tjpsj.org/index.php/tjps/article/view/1164MDAoxidative stress markerblood groupmontelukast drug
spellingShingle Jwad Ali Saleh
Shakir Mahmoud Suleiman
Zaidan Jayed Zaidan
Determination of MDA as oxidative stress marker and most common type of blood group in asthmatic patients before and after treatment with montelukast drug.
Tikrit Journal of Pure Science
MDA
oxidative stress marker
blood group
montelukast drug
title Determination of MDA as oxidative stress marker and most common type of blood group in asthmatic patients before and after treatment with montelukast drug.
title_full Determination of MDA as oxidative stress marker and most common type of blood group in asthmatic patients before and after treatment with montelukast drug.
title_fullStr Determination of MDA as oxidative stress marker and most common type of blood group in asthmatic patients before and after treatment with montelukast drug.
title_full_unstemmed Determination of MDA as oxidative stress marker and most common type of blood group in asthmatic patients before and after treatment with montelukast drug.
title_short Determination of MDA as oxidative stress marker and most common type of blood group in asthmatic patients before and after treatment with montelukast drug.
title_sort determination of mda as oxidative stress marker and most common type of blood group in asthmatic patients before and after treatment with montelukast drug
topic MDA
oxidative stress marker
blood group
montelukast drug
url https://tjpsj.org/index.php/tjps/article/view/1164
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AT shakirmahmoudsuleiman determinationofmdaasoxidativestressmarkerandmostcommontypeofbloodgroupinasthmaticpatientsbeforeandaftertreatmentwithmontelukastdrug
AT zaidanjayedzaidan determinationofmdaasoxidativestressmarkerandmostcommontypeofbloodgroupinasthmaticpatientsbeforeandaftertreatmentwithmontelukastdrug