Histological and histochemical changes of the skeletal muscle in human chronic Chagas' disease
Gastrocnemius muscle biopsies were performed in 7 subjects with chronic Chagas' disease. On clinical and laboratory grounds the selected patients were judged to be healthy, being the only abnormality found the presence of positive serum tests for Chagas' disease. Fibre type grouping of eit...
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| Format: | Article |
| Language: | English |
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Thieme Revinter Publicações
1978-12-01
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| Series: | Arquivos de Neuro-Psiquiatria |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1978000400006&lng=en&tlng=en |
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| author | Analia Taratuto M. A. Pagano Teresa Fumo Olga P. Sanz R. E. P. Sica |
| author_facet | Analia Taratuto M. A. Pagano Teresa Fumo Olga P. Sanz R. E. P. Sica |
| author_sort | Analia Taratuto |
| collection | DOAJ |
| description | Gastrocnemius muscle biopsies were performed in 7 subjects with chronic Chagas' disease. On clinical and laboratory grounds the selected patients were judged to be healthy, being the only abnormality found the presence of positive serum tests for Chagas' disease. Fibre type grouping of either type I or type II was observed in 5 of the 7 patients. Furthermore, in 2 of the 5 patients showing muscle fibre groupings, angular fibres reacting with NADH and non-specific sterase were also found. These observations strongly suggest denervation associated with reinervation. This picture often can be observed in the skeletal muscle of patients with well compensated denervatory conditions who do not show clinical evidences of denervation. |
| format | Article |
| id | doaj-art-e04d38df40b04a228aff28e065b78865 |
| institution | Kabale University |
| issn | 1678-4227 |
| language | English |
| publishDate | 1978-12-01 |
| publisher | Thieme Revinter Publicações |
| record_format | Article |
| series | Arquivos de Neuro-Psiquiatria |
| spelling | doaj-art-e04d38df40b04a228aff28e065b788652025-08-20T03:26:09ZengThieme Revinter PublicaçõesArquivos de Neuro-Psiquiatria1678-42271978-12-0136432733110.1590/S0004-282X1978000400006S0004-282X1978000400006Histological and histochemical changes of the skeletal muscle in human chronic Chagas' diseaseAnalia Taratuto0M. A. Pagano1Teresa Fumo2Olga P. Sanz3R. E. P. Sica4Hospital General de Agudos J. M. Ramos MejíaHospital General de Agudos J. M. Ramos MejíaHospital General de Agudos J. M. Ramos MejíaHospital General de Agudos J. M. Ramos MejíaHospital General de Agudos J. M. Ramos MejíaGastrocnemius muscle biopsies were performed in 7 subjects with chronic Chagas' disease. On clinical and laboratory grounds the selected patients were judged to be healthy, being the only abnormality found the presence of positive serum tests for Chagas' disease. Fibre type grouping of either type I or type II was observed in 5 of the 7 patients. Furthermore, in 2 of the 5 patients showing muscle fibre groupings, angular fibres reacting with NADH and non-specific sterase were also found. These observations strongly suggest denervation associated with reinervation. This picture often can be observed in the skeletal muscle of patients with well compensated denervatory conditions who do not show clinical evidences of denervation.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1978000400006&lng=en&tlng=en |
| spellingShingle | Analia Taratuto M. A. Pagano Teresa Fumo Olga P. Sanz R. E. P. Sica Histological and histochemical changes of the skeletal muscle in human chronic Chagas' disease Arquivos de Neuro-Psiquiatria |
| title | Histological and histochemical changes of the skeletal muscle in human chronic Chagas' disease |
| title_full | Histological and histochemical changes of the skeletal muscle in human chronic Chagas' disease |
| title_fullStr | Histological and histochemical changes of the skeletal muscle in human chronic Chagas' disease |
| title_full_unstemmed | Histological and histochemical changes of the skeletal muscle in human chronic Chagas' disease |
| title_short | Histological and histochemical changes of the skeletal muscle in human chronic Chagas' disease |
| title_sort | histological and histochemical changes of the skeletal muscle in human chronic chagas disease |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1978000400006&lng=en&tlng=en |
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