The Potential of Stem Cells in the Treatment of Skeletal Muscle Injury and Disease
Tissue engineering is a pioneering field with huge advances in recent times. These advances are not only in the understanding of how cells can be manipulated but also in potential clinical applications. Thus, tissue engineering, when applied to skeletal muscle cells, is an area of huge prospective b...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Stem Cells International |
| Online Access: | http://dx.doi.org/10.1155/2012/282348 |
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| _version_ | 1850166407408386048 |
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| author | S. MacLean W. S. Khan A. A. Malik S. Anand M. Snow |
| author_facet | S. MacLean W. S. Khan A. A. Malik S. Anand M. Snow |
| author_sort | S. MacLean |
| collection | DOAJ |
| description | Tissue engineering is a pioneering field with huge advances in recent times. These advances are not only in the understanding of how cells can be manipulated but also in potential clinical applications. Thus, tissue engineering, when applied to skeletal muscle cells, is an area of huge prospective benefit to patients with muscle disease/damage. This could include damage to muscle from trauma and include genetic abnormalities, for example, muscular dystrophies. Much of this research thus far has been focused on satellite cells, however, mesenchymal stem cells have more recently come to the fore. In particular, results of trials and further research into their use in heart failure, stress incontinence, and muscular dystrophies are eagerly awaited. Although no doubt, stem cells will have much to offer in the future, the results of further research still limit their use. |
| format | Article |
| id | doaj-art-e048e754c7634c8fab44a728257abb7a |
| institution | OA Journals |
| issn | 1687-966X 1687-9678 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Stem Cells International |
| spelling | doaj-art-e048e754c7634c8fab44a728257abb7a2025-08-20T02:21:28ZengWileyStem Cells International1687-966X1687-96782012-01-01201210.1155/2012/282348282348The Potential of Stem Cells in the Treatment of Skeletal Muscle Injury and DiseaseS. MacLean0W. S. Khan1A. A. Malik2S. Anand3M. Snow4University of Manchester, Manchester M13 9PL, UKInstitute of Orthpaedics and Musculoskeletal Science, Royal National Orthopaedic Hospital, Stanmore, Middlesex HA7 4LP, UKSpinal Deformity Unit, Royal National Orthopaedic Hospital, Brockley Hill, Stanmore, Middlesex HA7 4LP, UKStepping Hill Hospital, Stockport SK2 7JE, UKDepartment of Sports Inury, Royal National Orthopaedic Hospital, Birimingham B31 2AP, UKTissue engineering is a pioneering field with huge advances in recent times. These advances are not only in the understanding of how cells can be manipulated but also in potential clinical applications. Thus, tissue engineering, when applied to skeletal muscle cells, is an area of huge prospective benefit to patients with muscle disease/damage. This could include damage to muscle from trauma and include genetic abnormalities, for example, muscular dystrophies. Much of this research thus far has been focused on satellite cells, however, mesenchymal stem cells have more recently come to the fore. In particular, results of trials and further research into their use in heart failure, stress incontinence, and muscular dystrophies are eagerly awaited. Although no doubt, stem cells will have much to offer in the future, the results of further research still limit their use.http://dx.doi.org/10.1155/2012/282348 |
| spellingShingle | S. MacLean W. S. Khan A. A. Malik S. Anand M. Snow The Potential of Stem Cells in the Treatment of Skeletal Muscle Injury and Disease Stem Cells International |
| title | The Potential of Stem Cells in the Treatment of Skeletal Muscle Injury and Disease |
| title_full | The Potential of Stem Cells in the Treatment of Skeletal Muscle Injury and Disease |
| title_fullStr | The Potential of Stem Cells in the Treatment of Skeletal Muscle Injury and Disease |
| title_full_unstemmed | The Potential of Stem Cells in the Treatment of Skeletal Muscle Injury and Disease |
| title_short | The Potential of Stem Cells in the Treatment of Skeletal Muscle Injury and Disease |
| title_sort | potential of stem cells in the treatment of skeletal muscle injury and disease |
| url | http://dx.doi.org/10.1155/2012/282348 |
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