A case report: Endobronchial ultrasound guided biopsy of radiographically normal size thoracic lymph nodes supporting diagnosis of cardiac sarcoidosis
Sarcoidosis is a rare chronic granulomatous disease with unknown etiology. Definite diagnosis of cardiac sarcoidosis (CS) is especially difficult to establish. Several guidelines exist to make a diagnosis of CS but those have not been clinically validated. Despite the high specificity of endomyocard...
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Elsevier
2025-01-01
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| Series: | Respiratory Medicine Case Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213007124001692 |
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| author | Jee Young You Manuel L. Ribeiro Neto |
| author_facet | Jee Young You Manuel L. Ribeiro Neto |
| author_sort | Jee Young You |
| collection | DOAJ |
| description | Sarcoidosis is a rare chronic granulomatous disease with unknown etiology. Definite diagnosis of cardiac sarcoidosis (CS) is especially difficult to establish. Several guidelines exist to make a diagnosis of CS but those have not been clinically validated. Despite the high specificity of endomyocardial biopsy, its sensitivity is low, and the severity of potential complications is high. Thus, we present 63-year-old male who was diagnosed with CS with the endobronchial ultrasound (EBUS) transbronchial needle aspiration (TBNA) of intrathoracic lymph nodes which were non-enlarged without PET avidity. EBUS TBNA of radiographically normal appearing lymph nodes showed non-necrotizing granulomas. Given challenges of diagnosing CS, EBUS TBNA can be considered even in cases without obvious evidence of active pulmonary sarcoidosis. |
| format | Article |
| id | doaj-art-e0424c2bf9e5477da43a6268f75ef633 |
| institution | Kabale University |
| issn | 2213-0071 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Respiratory Medicine Case Reports |
| spelling | doaj-art-e0424c2bf9e5477da43a6268f75ef6332025-02-09T05:00:17ZengElsevierRespiratory Medicine Case Reports2213-00712025-01-0153102146A case report: Endobronchial ultrasound guided biopsy of radiographically normal size thoracic lymph nodes supporting diagnosis of cardiac sarcoidosisJee Young You0Manuel L. Ribeiro Neto1Corresponding author. 9500 Euclid Ave, A90, Respiratory Institute, Cleveland, OH, 44195, USA.; Department of Pulmonary and Critical Care Medicine, Respiratory Institute, Cleveland Clinic, Cleveland, OH, USADepartment of Pulmonary and Critical Care Medicine, Respiratory Institute, Cleveland Clinic, Cleveland, OH, USASarcoidosis is a rare chronic granulomatous disease with unknown etiology. Definite diagnosis of cardiac sarcoidosis (CS) is especially difficult to establish. Several guidelines exist to make a diagnosis of CS but those have not been clinically validated. Despite the high specificity of endomyocardial biopsy, its sensitivity is low, and the severity of potential complications is high. Thus, we present 63-year-old male who was diagnosed with CS with the endobronchial ultrasound (EBUS) transbronchial needle aspiration (TBNA) of intrathoracic lymph nodes which were non-enlarged without PET avidity. EBUS TBNA of radiographically normal appearing lymph nodes showed non-necrotizing granulomas. Given challenges of diagnosing CS, EBUS TBNA can be considered even in cases without obvious evidence of active pulmonary sarcoidosis.http://www.sciencedirect.com/science/article/pii/S2213007124001692Cardiac sarcoidosisEndobronchial ultrasoundTransbronchial needle aspirationNormal size lymph node |
| spellingShingle | Jee Young You Manuel L. Ribeiro Neto A case report: Endobronchial ultrasound guided biopsy of radiographically normal size thoracic lymph nodes supporting diagnosis of cardiac sarcoidosis Respiratory Medicine Case Reports Cardiac sarcoidosis Endobronchial ultrasound Transbronchial needle aspiration Normal size lymph node |
| title | A case report: Endobronchial ultrasound guided biopsy of radiographically normal size thoracic lymph nodes supporting diagnosis of cardiac sarcoidosis |
| title_full | A case report: Endobronchial ultrasound guided biopsy of radiographically normal size thoracic lymph nodes supporting diagnosis of cardiac sarcoidosis |
| title_fullStr | A case report: Endobronchial ultrasound guided biopsy of radiographically normal size thoracic lymph nodes supporting diagnosis of cardiac sarcoidosis |
| title_full_unstemmed | A case report: Endobronchial ultrasound guided biopsy of radiographically normal size thoracic lymph nodes supporting diagnosis of cardiac sarcoidosis |
| title_short | A case report: Endobronchial ultrasound guided biopsy of radiographically normal size thoracic lymph nodes supporting diagnosis of cardiac sarcoidosis |
| title_sort | case report endobronchial ultrasound guided biopsy of radiographically normal size thoracic lymph nodes supporting diagnosis of cardiac sarcoidosis |
| topic | Cardiac sarcoidosis Endobronchial ultrasound Transbronchial needle aspiration Normal size lymph node |
| url | http://www.sciencedirect.com/science/article/pii/S2213007124001692 |
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