Estimation of reproductive toxicity of the complex plant remedy "Tireoton"

To study the probable negative influence of the complex remedy "Tireoton" on the reproductive function of the laboratory animals the following tests have been carried out, namely the probable occurrence of embryo-toxicity, teratogenicity, foetotoxicity and its influence on the postnatal de...

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Main Authors: Y. G. Razuvaeva, S. M. Nikolaev, N. V. Verlan, I. P. Ubeeva, V. V. Ayusheeva
Format: Article
Language:Russian
Published: Scientific Сentre for Family Health and Human Reproduction Problems 2016-04-01
Series:Acta Biomedica Scientifica
Subjects:
Online Access:https://www.actabiomedica.ru/jour/article/view/172
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author Y. G. Razuvaeva
S. M. Nikolaev
N. V. Verlan
I. P. Ubeeva
V. V. Ayusheeva
author_facet Y. G. Razuvaeva
S. M. Nikolaev
N. V. Verlan
I. P. Ubeeva
V. V. Ayusheeva
author_sort Y. G. Razuvaeva
collection DOAJ
description To study the probable negative influence of the complex remedy "Tireoton" on the reproductive function of the laboratory animals the following tests have been carried out, namely the probable occurrence of embryo-toxicity, teratogenicity, foetotoxicity and its influence on the postnatal development of the laboratory animals progeny. The experiments have been carried out of the white Wistar rats. It has been established that the "Tireoton" at the doses of 75 and 750 mg/kg has no embryotoxic, teratogenic and fetotoxical effect. The introduction of the "Tireoton" at the dose of 750 mg/kg since 6th to 19th day of pregnancy does not influence on the postnatal development of white rats progeny.
format Article
id doaj-art-e03da5ecdfe5427085a2223efa574760
institution Kabale University
issn 2541-9420
2587-9596
language Russian
publishDate 2016-04-01
publisher Scientific Сentre for Family Health and Human Reproduction Problems
record_format Article
series Acta Biomedica Scientifica
spelling doaj-art-e03da5ecdfe5427085a2223efa5747602025-08-20T03:56:54ZrusScientific Сentre for Family Health and Human Reproduction ProblemsActa Biomedica Scientifica2541-94202587-95962016-04-0112606310.12737/20618172Estimation of reproductive toxicity of the complex plant remedy "Tireoton"Y. G. Razuvaeva0S. M. Nikolaev1N. V. Verlan2I. P. Ubeeva3V. V. Ayusheeva4Buryat State UniversityIrkutsk State Medical Academy of Continuing Education; Buryat State UniversityIrkutsk State Medical Academy of Continuing EducationIrkutsk State Medical Academy of Continuing Education; Buryat State UniversityInstitute of General and Experimental Biology SB RASTo study the probable negative influence of the complex remedy "Tireoton" on the reproductive function of the laboratory animals the following tests have been carried out, namely the probable occurrence of embryo-toxicity, teratogenicity, foetotoxicity and its influence on the postnatal development of the laboratory animals progeny. The experiments have been carried out of the white Wistar rats. It has been established that the "Tireoton" at the doses of 75 and 750 mg/kg has no embryotoxic, teratogenic and fetotoxical effect. The introduction of the "Tireoton" at the dose of 750 mg/kg since 6th to 19th day of pregnancy does not influence on the postnatal development of white rats progeny.https://www.actabiomedica.ru/jour/article/view/172potentilla alba lscutellaria baicalensis georgirhodiola rosea lcomplex plant remedypotentilla alba lscutellaria baicalensis georgirhodiola rosea lembryo-toxicityteratogenicityfoetotoxicitypostnatal development
spellingShingle Y. G. Razuvaeva
S. M. Nikolaev
N. V. Verlan
I. P. Ubeeva
V. V. Ayusheeva
Estimation of reproductive toxicity of the complex plant remedy "Tireoton"
Acta Biomedica Scientifica
potentilla alba l
scutellaria baicalensis georgi
rhodiola rosea l
complex plant remedy
potentilla alba l
scutellaria baicalensis georgi
rhodiola rosea l
embryo-toxicity
teratogenicity
foetotoxicity
postnatal development
title Estimation of reproductive toxicity of the complex plant remedy "Tireoton"
title_full Estimation of reproductive toxicity of the complex plant remedy "Tireoton"
title_fullStr Estimation of reproductive toxicity of the complex plant remedy "Tireoton"
title_full_unstemmed Estimation of reproductive toxicity of the complex plant remedy "Tireoton"
title_short Estimation of reproductive toxicity of the complex plant remedy "Tireoton"
title_sort estimation of reproductive toxicity of the complex plant remedy tireoton
topic potentilla alba l
scutellaria baicalensis georgi
rhodiola rosea l
complex plant remedy
potentilla alba l
scutellaria baicalensis georgi
rhodiola rosea l
embryo-toxicity
teratogenicity
foetotoxicity
postnatal development
url https://www.actabiomedica.ru/jour/article/view/172
work_keys_str_mv AT ygrazuvaeva estimationofreproductivetoxicityofthecomplexplantremedytireoton
AT smnikolaev estimationofreproductivetoxicityofthecomplexplantremedytireoton
AT nvverlan estimationofreproductivetoxicityofthecomplexplantremedytireoton
AT ipubeeva estimationofreproductivetoxicityofthecomplexplantremedytireoton
AT vvayusheeva estimationofreproductivetoxicityofthecomplexplantremedytireoton