Growth factor receptor plasticity drives therapeutic persistence of metastatic breast cancer
Abstract Metastatic breast cancer (MBC) remains a therapeutic challenge due to the persistence of minimal residual disease (MRD) and tumor recurrence. Herein we utilize a model of MBC that is sensitive to inhibition of fibroblast growth factor receptor (FGFR), resulting in robust regression of pulmo...
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| Main Authors: | Mitchell Ayers, Marvis Monteiro, Aneesha Kulkarni, Julie W. Reeser, Emily Dykhuizen, Sameek Roychowdhury, Michael K. Wendt |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2025-04-01
|
| Series: | Cell Death and Disease |
| Online Access: | https://doi.org/10.1038/s41419-025-07591-3 |
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