Lethal Neural Tube Defects: Reports of Anencephaly and Craniorachischisis Cases and Literature Review

Neural tube defects are serious birth defects of the central nervous system that result from a multifaceted disruption of normal embryogenesis of the nervous system. Although largely preventable, they nonetheless pose a serious threat to global morbidity, disability, mortality, and financial expense...

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Main Authors: Alemayehu Shiferaw Lema, Jemila Salih Suleyman
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:Case Reports in Obstetrics and Gynecology
Online Access:http://dx.doi.org/10.1155/2023/4017625
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author Alemayehu Shiferaw Lema
Jemila Salih Suleyman
author_facet Alemayehu Shiferaw Lema
Jemila Salih Suleyman
author_sort Alemayehu Shiferaw Lema
collection DOAJ
description Neural tube defects are serious birth defects of the central nervous system that result from a multifaceted disruption of normal embryogenesis of the nervous system. Although largely preventable, they nonetheless pose a serious threat to global morbidity, disability, mortality, and financial expenses. Despite this, it has been neglected and has only been the subject of limited research until recently. Furthermore, surveillance efforts for neural tube defects remain limited, and no decline in defects has been documented in less developed countries. Here, we report two cases of craniorachischisis and one case of discordant twins for anencephaly. Moreover, the relevant works of literature that are necessary to understand and address this unrelenting phenomenon are provided.
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spelling doaj-art-e03901b0452444aea050053204e906f82025-08-20T02:21:28ZengWileyCase Reports in Obstetrics and Gynecology2090-66922023-01-01202310.1155/2023/4017625Lethal Neural Tube Defects: Reports of Anencephaly and Craniorachischisis Cases and Literature ReviewAlemayehu Shiferaw Lema0Jemila Salih Suleyman1Department of Forensic Medicine and ToxicologyDepartment of Forensic Medicine and ToxicologyNeural tube defects are serious birth defects of the central nervous system that result from a multifaceted disruption of normal embryogenesis of the nervous system. Although largely preventable, they nonetheless pose a serious threat to global morbidity, disability, mortality, and financial expenses. Despite this, it has been neglected and has only been the subject of limited research until recently. Furthermore, surveillance efforts for neural tube defects remain limited, and no decline in defects has been documented in less developed countries. Here, we report two cases of craniorachischisis and one case of discordant twins for anencephaly. Moreover, the relevant works of literature that are necessary to understand and address this unrelenting phenomenon are provided.http://dx.doi.org/10.1155/2023/4017625
spellingShingle Alemayehu Shiferaw Lema
Jemila Salih Suleyman
Lethal Neural Tube Defects: Reports of Anencephaly and Craniorachischisis Cases and Literature Review
Case Reports in Obstetrics and Gynecology
title Lethal Neural Tube Defects: Reports of Anencephaly and Craniorachischisis Cases and Literature Review
title_full Lethal Neural Tube Defects: Reports of Anencephaly and Craniorachischisis Cases and Literature Review
title_fullStr Lethal Neural Tube Defects: Reports of Anencephaly and Craniorachischisis Cases and Literature Review
title_full_unstemmed Lethal Neural Tube Defects: Reports of Anencephaly and Craniorachischisis Cases and Literature Review
title_short Lethal Neural Tube Defects: Reports of Anencephaly and Craniorachischisis Cases and Literature Review
title_sort lethal neural tube defects reports of anencephaly and craniorachischisis cases and literature review
url http://dx.doi.org/10.1155/2023/4017625
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