Dual upregulation of miRNA-143 and miRNA-506 in non-small cell lung cancer inhibits proliferation, motility, migration, and tumor growth

Dual upregulation of miRNA-143 and miRNA-506 in non-small cell lung cancer inhibits proliferation, motility, migration, and tumor growth

Lung cancer (LC) is the leading cause of cancer-related deaths worldwide and is primarily treated with chemotherapy or radiotherapy. The role of microRNAs (miRs) is increasingly studied in cancer therapeutics, as miRs can regulate multiple cancer-related pathways simultaneously. While numerous miRs...

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Bibliographic Details
Main Authors: Archana Shrestha, Md Anamul Haque, Prajesh Shrestha, Margarita Lamprou, Seetharama D. Jois, Constantinos M. Mikelis, George Mattheolabakis
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Drug Discovery
Subjects:
microRNA
lung cancer
lentiviral delivery
microRNA-143
microRNA-506
dual microRNA therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fddsv.2025.1584801/full
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