NAA10 (N-Alpha-Acetyltransferase 10): A Multifunctional Regulator in Development, Disease, and Cancer
NAA10 (N-alpha-acetyltransferase 10) is a pivotal enzyme in eukaryotic cells, serving as the catalytic subunit of the NatA complex, which is responsible for the N-terminal acetylation of approximately 40–50% of the human proteome. Beyond its canonical role in co-translational N-terminal acetylation,...
Saved in:
| Main Authors: | Zeng Quan Yang, Ion John Campeanu, Ivan Lopez, Manaal Syed, Yuanyuan Jiang, Hilda Afisllari |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2025-06-01
|
| Series: | Cells |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2073-4409/14/12/863 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
miR-342 suppresses the proliferation and invasion of acute myeloid leukemia by targeting Naa10p
by: Haiyan Wang, et al.
Published: (2019-12-01) -
Exploring the role of N-acetyltransferases in diseases: a focus on N-acetyltransferase 9 in neurodegeneration
by: Prajakta Deshpande, et al.
Published: (2025-10-01) -
Yin Yang 1 protein-activated N-acetyltransferase 10 drives cell malignant progression of osteosarcoma through ac4C acetylation of integrin β3
by: Fan Yang, et al.
Published: (2025-08-01) -
Histone Acetyltransferase MOF-Mediated AURKB K215 Acetylation Drives Breast Cancer Cell Proliferation via c-MYC Stabilization
by: Yujuan Miao, et al.
Published: (2025-07-01) -
Biological Function and Mechanism of NAT10 in Cancer
by: Yufeng Han, et al.
Published: (2025-02-01)