Digital spatial profiling identifies phospho-JNK as a biomarker for early risk stratification of aggressive prostate cancer

Digital spatial profiling identifies phospho-JNK as a biomarker for early risk stratification of aggressive prostate cancer

BackgroundProstate cancer (PCa) is a highly heterogeneous disease, ranging from indolent to highly aggressive forms. Ongoing research focuses on identifying new biomarkers to improve early risk stratification in PCa, addressing current limitations to accurately evaluate disease progression. A promis...

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Main Authors: Samaneh Eickelschulte, Adam Kaczorowski, Florian Janke, Anja Lisa Riediger, Olga Lazareva, Sarah Böning, Glen Kristiansen, Constantin Schwab, Albrecht Stenzinger, Holger Sültmann, Stefan Duensing, Anette Duensing, Magdalena Görtz
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Oncology
Subjects:
prostate cancer
digital spatial profiling (DSP)
p-JNK
risk stratification
biomarker discovery
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1572299/full
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