Conformational landscapes of rigid and flexible molecules explored with variable temperature ion mobility-mass spectrometry

Conformational landscapes of rigid and flexible molecules explored with variable temperature ion mobility-mass spectrometry

Abstract Understanding the effect of temperature to the structural integrity of proteins is relevant to diverse areas such as biotechnology and climate change. Variable temperature ion mobility-mass spectrometry (VT-IM-MS) can measure the effect of temperature on conformational landscapes. To deline...

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Bibliographic Details
Main Authors: Xudong Wang, Emma Norgate, Junxiao Dai, Florian Benoit, Tony Bristow, Richard M. England, Jason M. D. Kalapothakis, Perdita E. Barran
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-59065-x
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