Muco‐Penetrating Lipid Nanoparticles Having a Liquid Core for Enhanced Intranasal mRNA Delivery

Muco‐Penetrating Lipid Nanoparticles Having a Liquid Core for Enhanced Intranasal mRNA Delivery

Abstract Intranasal delivery of mRNA vaccines offers promising opportunities to combat airborne viruses like SARS‐CoV‐2 by provoking mucosal immunity, which not only defends against respiratory infection but also prevents contagious transmission. However, the development of nasal mRNA vaccines has b...

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Bibliographic Details
Main Authors: Nipuni Maniyamgama, Ki Hyun Bae, Zi Wei Chang, Jialing Lee, Melgious J. Y. Ang, Yong Jie Tan, Lisa F. P. Ng, Laurent Renia, Kevin P. White, Yi Yan Yang
Format: Article
Language:English
Published: Wiley 2025-03-01
Series:Advanced Science
Subjects:
intranasal
ionizable
liquid lipid nanoparticles
mRNA
muco‐penetrating
Online Access:https://doi.org/10.1002/advs.202407383
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